Vascular Flashcards
What is the definition of an aneurysm?
> 150% dilatation of its original diameter.
True aneurysms involve all layers
Pseudo-aneurysms are collections of blood around a vessel wall - haemtoma in the adventitia
Where are the common sites to have aneurysms?
Aorta (infra renal), iliac, femorl, popliteal
What is the definition of a AAA?
> 3cm across.
How are unruptured AAA treated?
Treat any HTN
Monitor aneurysm size
Elective surgery/ stenting - >5.5cm or growing by >0.5cm/6months
What are the causes of aneurysms?
Due to degeneration of the arterial media - particularly a reduction in elastin.
Contributing factors:
Elastin degradation due to increased levels of metalloproteinases
Flow dynamics
Hypertension
Atherosclerosis
Collagen defects
Genetic
Smoking
Infections and inflammation can play a part also (Takayasu’s aortitis, and syphilis)
What is the indication for a carotid endarterectomy?
Stensosis >70%.
Should be performed within 2 weeks of first presentation
What are the risks of carotid endarterectomy?
Neck haematoma 5% Cervical and cranial nerve injury 7% (hypoglossal, vagus, recurrent laryngeal, marginal mandibular and transverse cervical nerves) Stroke 2% MI False aneurysm Infection of prosthetic patch Death 1%
Which artery is normally affected in acute mesenteric ischemia?
Superior mesenteric artery:
supplies the small bowel and up to the splenic flexure of the large bowel
What is the classic triad of acute mesenteric ischemia?
Acute severe abdo pain, no abdominal signs, rapid hypovolaemia.
What causes acute mesenteric ischemia?
Arterial: thrombotic, embolic
Non occlusive (in renal failure or low CO)
Venous
Other: trauma, vasculitis, radiotherapy, strangulation
What causes chronic colonic ischemia?
Low flow in the inferior mesenteric artery
What are the causes of Raynaud’s?
SLE Systemic sclerosis RA Cold Aggluntins Polycythaemia Oral contraceptives B blockers Occupational - vibrating tools Cervical rib
Describe the colour changes seen in Raynaud’s.
White - digital artery spasm causes blanching
Blue - accumulation of deoxygenated blood
Red - reactive hyperaemia
What are the signs of acute limb ischemia?
Pale Pulseless Painful Paralysed Paraesthetic Perishingly cold
If fixed mottling occurs this implies irreversibility
What are the causes of acute limb ischemia?
Thromobis in situ
Emboli - AF, atrial myxoma, underlying malignancy
Aneurysmal disease
Trauma
What is the management of acute limb ischemia?
Give heparin and resuscitate with IV fluids
Angiography
Either local thrombolysis or embolectomy