Various Mechanisms that Prevent Blood Loss Flashcards
What Term?
(a) A sequence of responses that stops bleeding when blood vessels are injured.
(b) The hemostatic response must be quick, localized to the region of damage, and carefully controlled.
hemostasis
-Be sure not to confuse the two words hemostasis and homeostasis.
What are he three mechanisms can reduce loss of blood from blood vessels.
(a) Vascular spasm
(b) Platelet plug formation
(c) Blood clotting (coagulation)
_______ can prevent hemorrhage from smaller blood vessels, but extensive hemorrhage from larger vessels usually requires medical intervention.
Hemostatis
When a blood vessel is damaged, the smooth muscle in its wall contracts immediately, a response called a _____. This reduces blood loss for several minutes to several hours, during which time the other hemostatic mechanisms begin to operate.
Vascular spasm
What is this?
When platelets come into contact with parts of a damaged blood vessel, their characteristics change drastically and they quickly come together to form a plug that helps fill the gap in the injured blood vessel wall.
Platelet Plug
True/False
A platelet plug can stop blood loss completely if the hole in a blood vessel is small enough
True
The process of clot formation
_______ is a series of chemical reactions that culminates in the formation of fibrin threads.
Coagulation
If blood clots too easily, the result can be _______, clotting in an unbroken blood vessel.
thrombosis
If Coagulation takes too long, _______ can result
hemorrhage
Clotting (coagulation) factors include:
1) Calcium ions (Ca2+)
2) Several enzymes that are made by liver cells and released into the blood.
3) Various molecules associated with platelets or released by damaged tissues.
Clotting occurs in three stages What stage is what?
______: Thrombin converts soluble fibrinogen (another plasma protein made by the liver) into insoluble fibrin.
______: Prothrombinase is formed.
______:Prothrombinase converts prothrombin (a plasma protein formed in the liver with the help of vitamin K) into the enzyme thrombin.
3.
1.
2.
True/False
Fibrin forms the threads of the clot, cigarette smoke does not contain substances that interfere with this step.
False
Cigarette smoke contains substances that interfere with this step
_______ is the consolidation or tightening of the fibrin clot. The fibrin threads attached to the damaged surfaces of the blood vessel gradually
contract as platelets pull on them.
Clot Retraction
In time, _______ form connective tissue in the ruptured area, and new endothelial cells repair the vessel lining.
fibroblasts
What causes a clot to begin to be digested and dissolve the fibrin threads to remove the clot
Blood and body tissues that activate plasminogen into plasmin.