Various Mechanisms that Prevent Blood Loss Flashcards

1
Q

What Term?

(a) A sequence of responses that stops bleeding when blood vessels are injured.
(b) The hemostatic response must be quick, localized to the region of damage, and carefully controlled.

A

hemostasis

-Be sure not to confuse the two words hemostasis and homeostasis.

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2
Q

What are he three mechanisms can reduce loss of blood from blood vessels.

A

(a) Vascular spasm
(b) Platelet plug formation
(c) Blood clotting (coagulation)

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3
Q

_______ can prevent hemorrhage from smaller blood vessels, but extensive hemorrhage from larger vessels usually requires medical intervention.

A

Hemostatis

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4
Q

When a blood vessel is damaged, the smooth muscle in its wall contracts immediately, a response called a _____. This reduces blood loss for several minutes to several hours, during which time the other hemostatic mechanisms begin to operate.

A

Vascular spasm

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5
Q

What is this?
When platelets come into contact with parts of a damaged blood vessel, their characteristics change drastically and they quickly come together to form a plug that helps fill the gap in the injured blood vessel wall.

A

Platelet Plug

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6
Q

True/False

A platelet plug can stop blood loss completely if the hole in a blood vessel is small enough

A

True

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7
Q

The process of clot formation

_______ is a series of chemical reactions that culminates in the formation of fibrin threads.

A

Coagulation

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8
Q

If blood clots too easily, the result can be _______, clotting in an unbroken blood vessel.

A

thrombosis

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9
Q

If Coagulation takes too long, _______ can result

A

hemorrhage

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10
Q

Clotting (coagulation) factors include:

A

1) Calcium ions (Ca2+)
2) Several enzymes that are made by liver cells and released into the blood.
3) Various molecules associated with platelets or released by damaged tissues.

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11
Q

Clotting occurs in three stages What stage is what?
______: Thrombin converts soluble fibrinogen (another plasma protein made by the liver) into insoluble fibrin.
______: Prothrombinase is formed.
______:Prothrombinase converts prothrombin (a plasma protein formed in the liver with the help of vitamin K) into the enzyme thrombin.

A

3.
1.
2.

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12
Q

True/False

Fibrin forms the threads of the clot, cigarette smoke does not contain substances that interfere with this step.

A

False

Cigarette smoke contains substances that interfere with this step

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13
Q

_______ is the consolidation or tightening of the fibrin clot. The fibrin threads attached to the damaged surfaces of the blood vessel gradually
contract as platelets pull on them.

A

Clot Retraction

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14
Q

In time, _______ form connective tissue in the ruptured area, and new endothelial cells repair the vessel lining.

A

fibroblasts

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15
Q

What causes a clot to begin to be digested and dissolve the fibrin threads to remove the clot

A

Blood and body tissues that activate plasminogen into plasmin.

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16
Q

A blood clot, bubble of air, fat from broken bones, or a piece of debris transported by the bloodstream is called an ______

A

Embolus

17
Q

Clotting in an unbroken blood vessel is called _____

A

Thrombus