variable/constant and antibodies Flashcards
what binds to the variable region
antibodies
variable region forms antigen
epitope binding site
variable region can be produced
to bind to every possible isotope
the constant region determines
destination of antibody and its type
5 types of antibodies
IGM, IGG, IGA, IGE, IGD
Antibody Primary Response
IGM produced first, quickly after exposure and IGM is higher concentration and lasts longer
Antibody Secondary Response
Igg goes wild lots more Igg but takes mjore time and lasts longer
IGm
first to appear in circulation
indicates recent infection
5 chains
IGG
gamma globulin
major circulating antibody
provides immunity to fetus and newborn
IGA
resistance in respiratory and gastrointestinal tracts
secrete antibody
found mucus, tears, saliva breast milk
IGE
allergic reactions
IGD
is the b cell receptor