Parts of Influenza (A)

Question 1

what is neuraminidase?

Answer 1

a spike protein

Question 2

what does neuraminidase allow?

Answer 2

virus to be released from cell

Question 3

How many types of neuraminidase?

Answer 3

9 types

Question 4

what is hemagglutinin

Answer 4

a spike protein

Question 5

Hemagglutinin attachment and what it does

Answer 5

attaches to cell, determines host range and tissue tropism

Question 6

how many types of hemagglutinin

Answer 6

15 types

Question 7

hemmagglutinin determines whether virus will bind to alpha…

Answer 7

alpha 2-3 sa or alpha 2,6-SA

Question 8

H5N1 virus has how many…

Answer 8

5 hemagglutinin and 1 neuraminidase

Question 9

antigenic drift is

Answer 9

continual gradual change in antigens (H & N change slightly)

Question 10

reason for yearly flu season and new shots

Answer 10

antigenic drift

Question 11

what is antigenic shift?

Answer 11

major changes greater than 50%, new arrangement of spike proteins

Question 12

when there is reassortment from simulatneous infections of two different virus in 1 cell this is

Answer 12

antigenic shift

Question 13

this occurs every 20 years or so and is the reason for large pandemics

Answer 13

antigenic shift

Question 14

we usually do not have prior immunity when there is

Answer 14

antigenic shifts