Vander

Question 1

What does NE bind to on the kidney? Where? What are its actions?

Answer 1

Binds to Alpha-1 receptors in the tubules

- can cause constriction of afferent and efferent arterioles

Question 2

What does ADH do to UT1 urea transporter?

Answer 2

Upregulates it

- this increases the interstium osmolarity and thus increases water resorption

Question 3

What does increase in PTH do to phosphate?

Answer 3

Increases it secretion

- thus decreases serum phosphate levels

Question 4

What does phosphate do in the filtrate?

Answer 4

binds to H+

• carrier of H+
• PTH released in response to acidosis

Question 5

What and where does the affects of PTH have on Ca2+?

Answer 5

Increases adenylate cyclase

- increases Ca2+ resorption in the distal tubules

Question 6

Where is mg resorbed at?

Answer 6

PCT
Thick ascending
Distal tubule

Question 7

Does it compete with anything?

Answer 7

Yes Ca2+ in distal tubule

• Hypercalcemia leads inhibits Mg resorption
• Vice versa

Question 8

What could one expect in the urine after treatment of torsades?

Answer 8

Hypercalciuria

Question 9

What does ECF volume expansion result in in terms of HC03?

Answer 9

decrease Reabsorption