Validity and Reliability of screening tests

Question 1

Natural history of disease

Answer 1

nature of the disease and how it progresses

Question 2

True positive

Answer 2

Tests correctly report disease presence when disease is present

Question 3

False Postive

Answer 3

Test incorrectly reports disease presence when there is no disease

Question 4

False Negative

Answer 4

Test incorrectly reports absence of disease when disease is present

Question 5

Internal Validity

Answer 5

Whether the study measures what it is supposed to measure

Question 6

External validity

Answer 6

Generalizability of the results to other populations

Question 7

Reliability

Answer 7

ability of test results being replicated if the test is repeated

Question 8

Probability

Answer 8

The study of the laws of chance

Question 9

Sensititivy

Answer 9

Tests ability to yield negative result when the person does not have the condition

Question 10

Gold Standard

Answer 10

Test with 100% sensitivity and specificity

Question 11

Positive predictive value

Answer 11

Probability of the person being free of disease when the screening test or diagnostic test is negative

Question 12

Negative predictive value

Answer 12

Probably of the person being disease from when the screening test or diagnostic test is negative

Question 13

Clinically significant

Answer 13

Referring to results that have clinical significance

Question 14

Likelihood Ratio

Answer 14

Combines sensitivity and specificity data to help the clinician quantify how much the odds of disease change based on a positive of negative test result