Vaders Renal Phys - Renal functions

Question 1

Vander’s Renal Physiology

Answer 1

Chapter 1 - Renal Functions, Basic Processes and Anatomy

Question 2

What is ‘balance’

Answer 2

for an individual cell all substances that enter or that are produced by the cell must be exactly
equal to the same substances which leave or are metabolized by the cell- if not the cell will die due to uncontrolled volume.

inputs and outputs are exactly equal,
Maintaining the steady state requires energetic input

Question 3

What are the 7 functions of the kindey

Answer 3

1. Regulation of water and electrolyte balance
   2 Regulation of BP and extracellular fluid volume
2. Excretion of metabolic waste and foreign substances
3. Regulation of RBC production
4. Regulation of acid-base
5. Regulation of Vit D production and regulation
6. gluconeogenesis

Question 4

How do the kidneys affect BP

Answer 4

1. determine blood volume
2. hormonal change resulting in SVR

Question 5

What causes a release of EPO?

Answer 5

Local decrease in tissue O2
Anaemia, decreased renal blood flow,

During CKD renal metabolism decrease resulting in more O2 which means EPO is not released appropriately