Vaccines Flashcards
What is the immune system’s first line of defence?
Innate immune system
What is the immune system’s second line of defence?
Adaptive immune system
Which immune system has a memory response?
Adaptive immune system
Which immune system recognises conserved PAMP as opposed to specific antigens?
Innate immune system
What is Somatic hyper mutation ?
Increased affinity of an antigen to an antibody
Which white blood cells begin the process of somatic hypermutation?
B- cells
What is isotope switching?
Changing an antibody from IGM to IGG
What are two examples of whole vaccines ?
Live attenuated vaccines
Killed pathogen vaccines
What is used to kill pathogens in killed pathogens vaccine?
Heat
Formalin
Name three types of fractional vaccines
Subunit vaccines
Toxoid vaccines
Polysaccharide vaccines
Name three types of DNA techniques
DNA vaccines
Viral vectors
Recombinant vaccines
What type of bacteria is Bordetella ?
Gram negative coccobacilli
What does Bordettela pertussis cause?
Whooping cough
