Antimicrobial Agents

Question 1

What do bactericidal drugs do?

Answer 1

Kill bacteria

Question 2

What do bacteriostasis drugs do?

Answer 2

Inhibits the growth of bacteria

Question 3

What are the four target sites of anti microbial agents ?

Answer 3

Cell wall synthesis
Protein synthesis
Nuclei acid synthesis
Cell membrane function

Question 4

What do microbial agents target in cell wall synthesis ?

Answer 4

Peptidoglycan

Question 5

What are two types of antibiotics used to target cell wall synthesis ?

Answer 5

Beta Lactams
Glycopeptides

Question 6

What are four types of Beta lactams ?

Answer 6

Penicillin
Cephalosporins
Monobactams
Carbapenems

Question 7

What are two types of Glycopeptides ?

Answer 7

Vancomycin
Teicoplanin

Question 8

Which antibodies target cell membrane function ?

Answer 8

Polymixins
Polyenes

Question 9

Which antibiotic is used to target cell membrane in fungi?

Answer 9

Polyenes

Question 10

Which antibiotics inhibit DNA synthesis?

Answer 10

Quinolones
Nalidixic acids

Question 11

Which antibiotics target 50s subunit of the ribosome (to inhibit protein synthesis) ?

Answer 11

Erythromycin
Chloramphenicol

Question 12

Which antibiotics target 30s subunit of the ribosomes (to inhibit protein synthesis)?

Answer 12

Tetracycline
Gentamicin

Question 13

Which antibiotics inhibit folic acid synthesis (prevents PABA from converting into folic) ?

Answer 13

Sulphonamides
Trimethoprim

Question 14

What antibiotic is used to treat URTI, Syphilis and meningitis?

Answer 14

Penicillin G/ Benzylpenicillin G

Question 15

Which microbes is Penicillin G active against?

Answer 15

S- Streptococci
T- Treponema pallidum
A- Anaerobes
N- Neisseria meningitides

Question 16

Which microbes is Ampicillin active against?

Answer 16

SAME as Penicillin PLUS:

S- Some enterobacteriacea
H- Haemophilus influenzae
E- Enterococcus species

Question 17

Which microbes is Piperacillin active against?

Answer 17

SAME as Ampicillin but also covers:

Pseudomonas aeruginosa