Vaccinations Inductory Flashcards
Vaccines are hailed as one of the greatest global health achievements…
avoiding an estimated 2-3 million deaths per year (WHO) and significantly reduce child mortality
The primary purpose of vaccinations
is to protect the individual from infectious diseases that can cause significant harm
Herd immunity
-When an individual is vaccinated, they become less of a threat to others as the disease cannot spread as widely, reducing outbreaks, reducing the reservoir of susceptible people, and ultimately leading to the eradication of the disease-causing agent
-Herd immunity is extremely important as it protects those who are vulnerable or cannot be vaccinated (infants, elderly, pregnant women, immunosuppressed).
Babies lack immunity, and older people’s immunity declines over time
Some groups are more susceptible to infectious diseases, or the risk of serious harm is higher; pregnant women and those with co-morbidities. Social changes, where one is introduced to a different environment or different people increases the risk of exposure to previously unseen infectious diseases; when children start school or young people start university, vaccines are recommended.
The prevalence of an infectious disease is affected by the environment
in the UK, the influenza virus is common in winter because it thrives when temperatures are lower. Sudden outbreaks of a disease, prevention of other risks related to the disease and the desire for herd immunity against an infectious agent push the need for vaccines.
The cost of mass manufacturing of a vaccine must be taken into consideration against the effectiveness of the programme. If the cost is high with poor immunity rates, the vaccine will not be brought to market.
There are risks with vaccines. In most cases….
the recipient will develop a mild illness in response to the vaccine (fever, rash) and pain or swelling at the injection site. Sometimes, the vaccine fails to give a sufficient immune response and in very rare cases (1 in a million), anaphylaxis will occur due to excipient or antigen related to allergen.
New vaccines
are required because of recent antibiotic resistance, the threat of new zoonotic pathogens, and because prophylaxis is better than a cure.