Vaccinations Flashcards
2 general responses of immune system
-activate cell to destroy harmful cell(cell to cell interaction)
-activate antibodies(bind to antigen to make them less harmful)
what is an antibody
y-shaped immunoglobulin produced by plasma to fight antigens
order of antibody immune response
-antigen invades
-lymphocytes produce antibodies
-antibodies attach to and label antigen
-macrophage finds labeled cells and destroy them
job of antibodies
-recognize foreign molecules
-bind toxins and creating insoluble compound
-cover up virus attachment sites
5 main classes of immunoglobulins
G,M,A,D,E
what class of immunoglobulin to we care about most in the horse industry
igG
why are foals born with no antibodies
proteins are too large to pass through the placenta
how do foals acquire antibodies
through colostrum
how do foals absorb antibodies from colostrum
through specialized cells in the SI that disappear after 48 hours
what igG level do you want a foal to have after 24 hours?
below what level is critical?
you want greater than 800 mg/dL
below 400 mg/dL is critical
what type of immunity do foals get from colostrum
passive immunity
what could cause a foal to not get enough igGs after 25 hours
-mare dies
-poor quality colostrum
-leaks colostrum prior to foaling
ways to overcome a foals lack of access to good colostrum
-store extra colostrum
-use other mares
-plasma transfusions(requires several transfusions)
general side effects of diseases
-increases cost
-reduces performance
-limits growth
types of infectious diseases
parasitic
bacterial
viral
types of non infectious diseases
environmental
nutritional
genetic
what should you do before giving any type of drug or vaccine
make sure you have proper record keeping
T/F rubbing alcohol will not sterilize the area unless its allowed to sink in
TRUE
T/F sub Q injections are one of the most common injection types for horses
FALSE. its rarely used on horses
what length of needle should you use?
mature?
foal?
IV?
mature: 1.5”
foal: 1”
IV: 1” or 1.5”(shoburt prefers 1”)
why should you aspirate the syringe before giving an injection
it will help you know if your in the right place based on the presence or absence of blood
what factors may effect your vaccination schedule
geographic location
outbreaks
level of insect/rodent population
what type of vaccine are all tetanus vaccines, and mode of administration
killed virus, IM
schedule for tetanus vaccine
-2 initial doses 3-4 weeks apart
-annual booster
-broodmares 4-6 weeks prepartum