Vaccination & travel meds Flashcards
Common live vaccines
- BCG
- MMR
- Varicella
- Rotavirus
- Oral poliovirus
- Yellow fever
Schedules for HBV vaccination
D1: Birth
D2: 2 month
D3: 6 month
Adult boosters for those with nil evidence of immunity/past infection
Schedules for DTaP/Tdap vaccination
D1: 2 month
D2: 4 month
D3: 6 month
B1: 18 month
B2: 10-11 y.o. (Tdap)
Schedules for poliomyelitis vaccination
Same as HBV
D1: 2 month
D2: 4 month
D3: 6 month
B1: 18 month
B2: 10-11 y.o.
Schedules for Hib vaccination
D1: 2 month
D2: 4 month
D3: 6 month
B1: 18 month
Schedules for pneumococcal vaccination for children
D1: 4 month (PCV)
D2: 6 month (PCV)
B1: 12 month (PCV)
1-2 doses of PPSV only for those with specific medical conditions
Schedules for MMR vaccination
D1: 12 month
D2: 15 month
Adult MMR booster x 2 doses for those with nil evidence of immunity/past infection
Schedules for varicella vaccination
Same as MMR
D1: 12 month
D2: 15 month
Schedules for HPV vaccination
D1: 12-13 y.o.
D2: 1 year later
If no childhood vaccination done, 3 doses are needed
Schedules for influenza vaccination
- 1 dose/season for 6 months to up to 5 y.o.
- 1 dose/season for people above 5 y.o. with specific medical conditions
- 1 dose/season for everyone 65 y.o. and above
HBV vaccination for dialysis patients
- 4 dose series with Engerix-B
- 0, 1, 2, 6 months intervals
- 2 mL dose instead of 1 mL
Pneumococcal vaccination for adults
- Routine vaccination for adults 65 y.o. and above
- 1 x PCV, followed by 1 x PPSV at least 8 weeks later (immunocompromised) or 1 year later (rest)
- 1 x PPSV booster if 2 dose series completed before 65 y.o.
Tetanus vaccination for adults
For wound management:
- 1x Td/Tdap booster if 10 years gap (clean wound) or 5 years (all other wounds)
For pregnancy:
- 1 x Tdap booster
Varicella vaccination for adults
Only indicated if nil immunity demonstrated
- 1 dose if previously immunised
- 2 doses 4-8 weeks apart if no immunisation
Typhoid vaccination for travellers
IM/SC vaccine 2 weeks before travel
Efficacy lasts up to 2 years
Which medications should be avoided when administering oral typhoid vaccines?
- All antibiotics (within 3 days from immunisation)
- Mefloquine (avoid 8-24 hours after po mefloquine)
- Chloroquine (can be given tgt)
HAV vaccination recommendations
- Lowest age: 1 y.o.
- 2 doses schedule
- Second dose 6-12 months after 1st dose (max 18 months)
- No booster needed
Meningococcal vaccination recommendation
- Menactra (tetravalent)
- 9 months and up
- Single dose at least 10 days before travel; not more than 8 years from vaccination
- Booster after 3 years (<7 y.o.), after 5 years (7 y.o. and above)
MenB vaccine for serotype B only
- Not as travel vaccine
- Two dose series (1 month apart)
Rabies vaccine recommendations
- 3 dose series (0, 7, 21/28 days)
- For those with occupational exposure risk
- Higher risk exposure may require antibody titre check every 6 month-2 years
- 2 x boosters are only needed if bitten after completion of schedule
- 4 doses (0, 3, 7, 14 days) if not previously immunised and bitten
When are rabies immunoglobulin needed?
- Not immunised against rabies
- With severe transdermal wounds and contamination with saliva
- Bat bites
Japanese encephalitis vaccination
- For travels to endemic areas >1 month
IM for Ixiaro (NA, Europe, australia)
- 2 months and up
- 2 doses and 1 booster (1 year later, if needed)
SC for Imojev (Asia)
- 9 months and up
- 1 dose, booster (5 years later, if needed)
Yellow fever vaccination
- Liver attenuated
- Single SC dose at least 10 days before travel
- No booster (unless immunocompromised, pregnancy or HSC transplant)
Associated with increased risk of:
- Viscerotropic diseases
- Neutropenic diseases
Transmission of diseases by mosquitoes
- Japanese encephalitis (Culex; dusk to dawn)
- Yellow fever (Aedes; dawn to dusk)
- Malaria (Anopheles; dusk to dawn)
Drug of choice for malaria prophylaxis for P falciparum
- Atorvaquone-proguanil (Malarone)
- Doxycycline
Dosing for Malarone
- Start 1-2 days before
- Daily dosing
- Continue 1 week after
- Adults (>40 kg): 1 adult tablet
- Avoid in ESRF, pregnancy/breastfeeding,
Dosing for doxycycline
- Start 1-2 days before
- Daily dosing
- Continue 4 weeks after
Dosing for mefloquine
- Start 2-3 weeks before
- Weekly dosing
- Continue 4 weeks after
- Avoid in neuropsychiatric disease, QTc prolongation
Terminal prophylaxis of malaria
- Primaquine 30 mg daily for 2-3 weeks
- Not for pregnancy & G6PD deficiency (lower dose)
- Only indicated in those with prolonged exposure to P vivax
Dose of acetazolamide
- PO 125 mg q12 hours start 1 day before ascending
- Continued throughout ascend
- Continue for 1st 2 days at the same altitude
How long to avoid blood donation after traveling to malaria endemic countries
4 months
Monitor symptoms for up to 12 months