UWorld Questions Flashcards

1
Q

Most important risk factor for stroke?

A

Hypertension

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2
Q

Which type of hematoma crosses suture lines?

A

Subdural hematoma

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3
Q

Fetal hydantoin syndrome

A

Caused by mother use of carbamazepine or phenytoin. Microcephaly, cleft lip/palate, digital hypoplasia, hirsuitism.

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4
Q

Long term sequelae of bacterial meningitis?

A

Hearing loss, mental retardation, loss of cognitive function, seizures, spasticity or paralysis.

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5
Q

Creutzfeld Jacob Disease Symptoms.

A

Rapidly progressive dementia, ataxia, myoclonus, hypokinesia, bi/triphasic sharp waves on EEG.

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6
Q

What is preserved in brain death?

A

Deep tendon reflexes – no brain needed.

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7
Q

Symptoms of hypokalemia

A

Weakness and cramps in extremities. Broad flat t waves, u waves, can cause vfib or torsades.

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8
Q

What is biggest risk factor for development of cerebral palsy?

A

Prematurity before 32 weeks.

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9
Q

Most common form of cerebral palsy in premature infants?

A

Spastic diplegia. Hypertonia and spasticity in legs often with an equinovarus (down and in) deformity of the foot.

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10
Q

When to perform craniotomy after a epidural hematoma?

A

Cerebellar signs, pupil defect, GCS

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11
Q

What causes anterior cord syndrome?

A

Paraparasis, loss of pain and temp. Proprioception intact. Caused by a burst fracture of a vertebrae

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12
Q

Cauda equina syndrome

A

Motor loss on one side, variable sensory loss, urinary and fecal incontinence.

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13
Q

Wernicke’s encephalopathy

A

Due to malnutrition (lack of B1). Gait dysfunction, ocular problems, altered mental status.

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14
Q

Key indicator of dementia?

A

Impaired functioning with ADLs and IADLS

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15
Q

Multiple System Atrophy symptoms

A

Autonomic dysfunction with parkinsonism. AKA shy-drager syndrome.

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16
Q

Primidone

A

Antiepileptic that converts to phenobarbital. Can cause abdominal pain, hallucinations, headaches and dizziness.

17
Q

Cavernous sinus thrombosis

A

Infection can drain to the sinus because veins there are valveless. This can cause cavernous sinus thrombosis Causes headache periorbital edema, nerve palsies.

18
Q

Basal ganglia hemorrhage

A

Contralateral Hemiparesis and hemisensory loss.
Gaze palsy.
Homonymous hemianopsia.

19
Q

Cerebellar hemorrhage

A

NO hemiparesis.

+ ataxia, dysmetria, headache, facial weakness

20
Q

Thalamic hemorrhage

A

Contralateral hemiparesis and sensory loss. Eyes deviate towards the lesion. Nonreactive miotic pupils, upgaze palsy

21
Q

Prochlorperazine

A

Intravenous D2 antagonist used for nausea

22
Q

Niemann Pick Vs Tay Sachs

A

Niemann Pick disease – sphingomyelinase deficiency
Tay Sachs – hexosaminidase deficiency

Both have cherry red spot and protuberent abdomen

Niemann pick has hepatosplenomegaly and arreflexia.
Tay Sachs has no HSM and hyperreflexia.

23
Q

Causes of syringomyelia

A

Arnold chiari malformations

Spinal cord injury

24
Q

Central Cord syndrome

A

Hyperextension injury in elderly with spondylosis. Weakness in upper extremities, incomplete loss in lowers. Localized loss of pain and temp sensation.

25
Q

How to manage myesthenic crisis?

A

Pyridostigmine, then IVIG/plasmaphoresis AND glucocorticoids.

26
Q

How to distinguish absence seizure from complex partial seizure?

A

Complex partial seizure has post-ictal confusion.

27
Q

Most common infra vs supra tentorial neoplasm in children?

A

Both astrocytomas

28
Q

Treatment for patients with one brain met, or multiple?

A

One=surgical resection

Two=whole brain irradiation

29
Q

Peripheral vascular disease vs spinal stenosis

A

Spinal stenosis pain is present upon standing, not just with activity.

Spinal stenosis can paint a neurogenic claudication picture. Check pulses.