uworld key points

Question 1

acute graft rejection findings on histology

Answer 1

dense interstitial lymphocytic infiltrate occurs weeks after transplant, cell mediated process, tx= preventative immunosuppr drugs

Question 2

describe hyperacute rejection after transplant

Answer 2

acute cession of blood flow after joining the circulations, due to preformed ab to donor antigens

Question 3

ischemic damage on histology

Answer 3

patchy necrosis with granulation tissues

Question 4

chronic rejection of a transplant on histology

Answer 4

scant inflammatory cells and interstitial fibrosis T cell and B cell mediated (ab mediated too) occurs months to years after a solid organ transplant

Question 5