Uveitis

Question 0

Whats used for prophylaxis of pcp?

Answer 0

Bactrim

Question 1

Whats the fa finding in birdshot?

Answer 1

“Quenching” of the vessels= dye leaving vessels quickly

Question 2

Rx for jia

Answer 2

Mtx bc have longest safety record w it and dosing is q week

Second line tnfa inhibitor

Question 3

Name tnf alpha inhibitor

Answer 3

Infliximab

Adilibumab (humira)

Question 4

Apmppe

Unilat or bilater?

Answer 4

Following viral illness–> Bilat bc its an autoimmune attack of choriocapillaris–> infarcts rpe
Generally good prognosis

Question 5

Mutton fat KPs aggregates of what type of cell?

Answer 5

macrophages

Question 6

can pars planitis cause vh and if so how?

Answer 6

yes.

vasculitis–>neo–>vh

Question 7

Whats a bad compliaction of ra?

Answer 7

Scleromalacia perforans

Question 8

what type of rd do you get in pars planitis?

Answer 8

rrd or trd from vasculitis and contraction of neo

Question 9

whats a synonym for C-ANCA?

Answer 9

anti-proteinase 3

Question 10

what are the main SE of cyclosporine and whats the mechanism?

Answer 10

T cell inhibitor

HTN and renal dz

Question 11

when psoriatic arthritis develops wo the artritis part, how does it present differently in the eye?

Answer 11

bilateral
older pt
requires oral NSAIDS

Question 12

If you are on cyclophosphamide, your chance of leukemia is 13x higher if you have what underlying blood disorder?

Answer 12

polycythemia rubra vera

Question 13

MTX mech and SE

Answer 13

folate analogue

GI upset, hepatotoxicity

Question 14

Myopentolate mofetil, brand name, mech of axn and SE

Answer 14

cellcept
inhibits Purine synthesis
diarrhea, GI ulceration

Question 15

what kind of bug is H flu?

Answer 15

gram neg coccus

Question 16

what bug may be responsible for fuchs heterochromic iridocyclitis?

Answer 16

rubella or CMV

Question 17

what kind of bug is bartonella?

Answer 17

gram negative rod

Question 18

besides being bad in MS, what other bad thing can infliximab do?

Answer 18

cause someone to develop lupus and become ana+

Question 19

whats the best treatment for serpiginous, whats the second option if pt is young?

Answer 19

1) cyclophosphamide is best but cant use it If pt wants to have kids
alternative is prednisone, cyclosporine and azathioprine

Question 20

whats the term for how the eye responds to a pathogen in a subdued way?

Answer 20

ACAID- anterior chamber associated immune deviation

Question 21

whats the role of fas ligand in the eye?

Answer 21

fas ligand- the eyes have it!

helps dampen the immune response

Question 22

whats a sysnonym of reactive arthritis?

Answer 22

reiters

Question 23

whats circinate balanitis?

Answer 23

penis rash around head of penis associated with reiters

Question 24

whatst the kveim test?

Answer 24

skin test for sarcoid in which ground up spleen is injected into pt and see if have granulomatous reaction

Question 25

what type of immune rxn is ocp?

Answer 25

type 2- ab DIRECTLY against surface

Question 26

heel spurs are a sign of what HLA B27 dz?

Answer 26

reactive arthritis (reiters)

Question 27

bony destruction of the orbital rim

Answer 27

Langerhans histocytosis

Question 28

kid w unilateral pig changes, pale nerve. UNILATERAL what could it be

Answer 28

DUSN

Question 29

what causes loss of vision in congenital rubella?

Answer 29

cataracts and microphthalmos

Question 30

pt with apmppe comes in with neuropathy- what should you do next?

Answer 30

mra! | apmppee is associated with cerebral vasculitis

Question 31

what are the clues that an anterior uveitis might be viral?

Answer 31

iris atrophy | stellate KP not confined to vogts triangle

Question 32

why cant you keep kids on steroids long?

Answer 32

growth retardation | premature closure of epithysis

Question 33

how does relapsing polychondritis present

Answer 33

scleritis and inflammation of CARTILEDGE | ear tips, nose tip and joint pain

Question 34

name some sequelae of pars planitis

Answer 34

CME RRD VH Glaucoma

Question 35

what protein is expressed at the bow region of the lens as it is proliferating?

Answer 35

major intrinsic protein (MIP)

Question 36

whats the prophylaxis for mai?

Answer 36

rifabutin

Question 37

whats the prophlaxis for pcp?

Answer 37

bactrim

Question 38

for uveitic cataract if acrylic is not available, whats the next best choice?

Answer 38

heparin coated pmma

Question 39

leptospirosis can give false positive of what test?

Answer 39

rpr

Question 40

pt with lupus has brvo, they are at risk for what?

Answer 40

seizures (other cns stuff)

Question 41

kid with jia and band k with uncontrolled iop, whats the definitive surg procedure?

Answer 41

tube

Question 42

how does indomethacin work?

Answer 42

blocks cox

Question 43

what do corticosteroids block?

Answer 43

phospholipase a2

Question 44

besides rifabutin and cidofovir which drugs can cause uveitis?

Answer 44

metipranolol | bisphospinates (eg alendronate)

Question 45

which of the seronehative spondyloarthro[athies is MOST closely ass w HLAB27

Answer 45

ankylosing spondylitis others: chrons psoriatic artiritis reiters

Question 46

cysticercosis how to treat?

Answer 46

if actual cysts in retina- surgery | no cysts- thiobendazole

Question 47

most common SE of cyclophosphomide

Answer 47

hemorrhagic cystitis

Question 48

kids w sarcoid- what do they get more and wht do they get less?

Answer 48

erythema nodosum MORE rash- MORE lung involvemet - LESS

Question 49

list the steroid drops from strongest to weakest

Answer 49

dex PF= pred sodium phosphate FML Rimexolone

Question 50

when is a pt w chrons likely hlab27 +, when are they most likely -?

Answer 50

present w scleritis- likely - | present w acute iritis likely + and will get back pain