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Uveitis Flashcards

0
Q

Whats used for prophylaxis of pcp?

A

Bactrim

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1
Q

Whats the fa finding in birdshot?

A

“Quenching” of the vessels= dye leaving vessels quickly

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2
Q

Rx for jia

A

Mtx bc have longest safety record w it and dosing is q week

Second line tnfa inhibitor

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3
Q

Name tnf alpha inhibitor

A

Infliximab

Adilibumab (humira)

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4
Q

Apmppe

Unilat or bilater?

A

Following viral illness–> Bilat bc its an autoimmune attack of choriocapillaris–> infarcts rpe
Generally good prognosis

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5
Q

Mutton fat KPs aggregates of what type of cell?

A

macrophages

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6
Q

can pars planitis cause vh and if so how?

A

yes.

vasculitis–>neo–>vh

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7
Q

Whats a bad compliaction of ra?

A

Scleromalacia perforans

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8
Q

what type of rd do you get in pars planitis?

A

rrd or trd from vasculitis and contraction of neo

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9
Q

whats a synonym for C-ANCA?

A

anti-proteinase 3

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10
Q

what are the main SE of cyclosporine and whats the mechanism?

A

T cell inhibitor

HTN and renal dz

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11
Q

when psoriatic arthritis develops wo the artritis part, how does it present differently in the eye?

A

bilateral
older pt
requires oral NSAIDS

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12
Q

If you are on cyclophosphamide, your chance of leukemia is 13x higher if you have what underlying blood disorder?

A

polycythemia rubra vera

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13
Q

MTX mech and SE

A

folate analogue

GI upset, hepatotoxicity

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14
Q

Myopentolate mofetil, brand name, mech of axn and SE

A

cellcept
inhibits Purine synthesis
diarrhea, GI ulceration

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15
Q

what kind of bug is H flu?

A

gram neg coccus

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16
Q

what bug may be responsible for fuchs heterochromic iridocyclitis?

A

rubella or CMV

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17
Q

what kind of bug is bartonella?

A

gram negative rod

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18
Q

besides being bad in MS, what other bad thing can infliximab do?

A

cause someone to develop lupus and become ana+

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19
Q

whats the best treatment for serpiginous, whats the second option if pt is young?

A

1) cyclophosphamide is best but cant use it If pt wants to have kids
alternative is prednisone, cyclosporine and azathioprine

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20
Q

whats the term for how the eye responds to a pathogen in a subdued way?

A

ACAID- anterior chamber associated immune deviation

21
Q

whats the role of fas ligand in the eye?

A

fas ligand- the eyes have it!

helps dampen the immune response

22
Q

whats a sysnonym of reactive arthritis?

A

reiters

23
Q

whats circinate balanitis?

A

penis rash around head of penis associated with reiters

24
Q

whatst the kveim test?

A

skin test for sarcoid in which ground up spleen is injected into pt and see if have granulomatous reaction

25
Q

what type of immune rxn is ocp?

A

type 2- ab DIRECTLY against surface

26
Q

heel spurs are a sign of what HLA B27 dz?

A

reactive arthritis (reiters)

27
Q

bony destruction of the orbital rim

A

Langerhans histocytosis

28
Q

kid w unilateral pig changes, pale nerve. UNILATERAL what could it be

A

DUSN

29
Q

what causes loss of vision in congenital rubella?

A

cataracts and microphthalmos

30
Q

pt with apmppe comes in with neuropathy- what should you do next?

A

mra!

apmppee is associated with cerebral vasculitis

31
Q

what are the clues that an anterior uveitis might be viral?

A

iris atrophy

stellate KP not confined to vogts triangle

32
Q

why cant you keep kids on steroids long?

A

growth retardation

premature closure of epithysis

33
Q

how does relapsing polychondritis present

A

scleritis and inflammation of CARTILEDGE

ear tips, nose tip and joint pain

34
Q

name some sequelae of pars planitis

A

CME
RRD
VH
Glaucoma

35
Q

what protein is expressed at the bow region of the lens as it is proliferating?

A

major intrinsic protein (MIP)

36
Q

whats the prophylaxis for mai?

A

rifabutin

37
Q

whats the prophlaxis for pcp?

A

bactrim

38
Q

for uveitic cataract if acrylic is not available, whats the next best choice?

A

heparin coated pmma

39
Q

leptospirosis can give false positive of what test?

A

rpr

40
Q

pt with lupus has brvo, they are at risk for what?

A

seizures (other cns stuff)

41
Q

kid with jia and band k with uncontrolled iop, whats the definitive surg procedure?

A

tube

42
Q

how does indomethacin work?

A

blocks cox

43
Q

what do corticosteroids block?

A

phospholipase a2

44
Q

besides rifabutin and cidofovir which drugs can cause uveitis?

A

metipranolol

bisphospinates (eg alendronate)

45
Q

which of the seronehative spondyloarthro[athies is MOST closely ass w HLAB27

A

ankylosing spondylitis

others:
chrons
psoriatic artiritis
reiters

46
Q

cysticercosis how to treat?

A

if actual cysts in retina- surgery

no cysts- thiobendazole

47
Q

most common SE of cyclophosphomide

A

hemorrhagic cystitis

48
Q

kids w sarcoid- what do they get more and wht do they get less?

A

erythema nodosum MORE
rash- MORE
lung involvemet - LESS

49
Q

list the steroid drops from strongest to weakest

A

dex
PF= pred sodium phosphate
FML
Rimexolone

50
Q

when is a pt w chrons likely hlab27 +, when are they most likely -?

A

present w scleritis- likely -

present w acute iritis likely + and will get back pain

written boards (13 decks)

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