Uvea Flashcards
How do you treat Uveitis?
Start treatment immediately Topical and systemic anti-inflammatory drugs- 2-4 weeks past resolution of signs Topical mydriatic
What topical anti-inflammatory drugs are indicated for use in Uveitis?
Topical steroids QID+ 1% prednisolone acetate (idael) 0.1% dexamethasone (penetrates well), but are often combined with Neo/Poly and causes bacterial resistance Topical NSAID: safer when concurrent corneal ulceration present but still delays epithelial healing. Drugs: Diclofenac- preferred with mild uveitis, or in hypermature cataracts Great to prevent or treat mild les-induced uveitis
What Systemic anti-inflammatory drugs are indicated for use in Uveitis?
Systemic NSAID- carprofen, meloxicam, firocoxib- avoid if hyphema/hemorrhage Systemic corticosteroid (used at an anti-inflammatory dose) Prednisone then taper. Optimal for posterior segment involvement. Use caution with systemic infectious disease
What topical Mydriatic is indicated for Uveitis?
Atropine- to reduce ciliary spasm pain. STabilizes blood-aqueous barrier. Tropicamide TID-QID- les spotent with shorter duration of action
What systemic anti-microbial drugs are indicated for Uveitis?
Doxycycline 10mg/kg PO SID x 21 days. May use if suspicious of bacterial infection or if perscribing oral corticosteroids.
What are sequelae to Uveitis
Cataract formation (uveitis is the most common cause of cataract formation in horses and small animals) Synechiation Lens luxation/subluxation Phthisis bulbi Secondary glaucoma
Persistent pupillary membranes treatment
no treatment needed. This is inherited in some dogs. May be genetic.
what is the difference between persistent pupillary membranes and synechia
PPMs- arise from iris collarette to lens, cornea, or other areas of the iris. Synechia- extend from pupillary margin of iris to lens or cornea
Uveal cysts cause and treatment
benign in most cases- not a tumor No treatment usually needed. Can aspirate with needle or deflate with diode laser if vision impact
Name the condition
Iris hypoplasia/Coloboma
Hypoplasia= thin iris tissue
Coloboma= focal absence of tissue, manifesting as a hole (Hole in the iris)
What is this an example of?
Iris atrophy
Common in middle-aged and older animals
May limit pupil constriciton- common cause of poor PLR and/or anisocoria in otherwise normal eyes
Thin iris or irregularity of pupillary margin
What species is a ciliary body adenoma/adenocarcinoma more common?
dogs> cats
What species is diffuse iris melanoma more common?
cat> dogs
What species is a melanocytoma/melanoma more common?
dog>cat
What metastatic uveal neoplasia is most common?
Lymphoma is the most common
