UTIs Flashcards
What are the main causes of obstruction to complete bladder emptying?
pregnancy
prostatic hypertrophy
renal calculi
tumours
strictures
What is the most common UTI pathogen?
Ecoli
What is the most common cause of someone developing a UTI?
ascending route from urethra to bladder
What is the difference between uncomplicated and complicated UTI?
uncomplicated = normal (anatomical and function) urinary tract
complicated = functional or anatomical abnormality (including catheters) - lower antibiotic threshold
What is an isolated UTI?
no previous UTI for 6mo
What is a recurrent UTI?
> 2 infections in 6mo or >3 in 12mo
What is relapsing UTI?
inadequate therapy
reinfection normally within same month (same organism)
Acute lower UTI symptoms
dysuria
urgency
frequency
Cystitis symptoms and signs
symptoms:
- frequency
- urgency
- suprapubic pain on postponing
- dysuria
- foul smelling, discoloured urine
- mild systemic upset
signs:
- temperature
- suprapubic tenderness
Cystitis investigations
urine dipstick
MSU for culture
Cystitis treatment
non-pharmacological (mild):
- fluids
- alkalinisation of urine (potassium citrate)
antibiotics:
- trimethoprim
- nitrofurantoin
- fosfomycin
- cefalexin
Uncomplicated UTI pathogens
Ecoli
other enterobacteriacae:
- proteus mirabilis
- K.pneumoniae
S.saprophyticus
What is the significance of S.saprophyticus infection?
only occur in urinary system
risk in pregnancy
Complicated UTI pathogens
Ecoli
other enterobacteriacae:
- proteus spp
- klebsiella spp
- citrobacter spp
- enterobacter spp
pseudomonas aeruginosa
enterococcus spp
Group B strep (if pregnant, need abx in labour)
candida spp
Where can UTIs come from?
ascending from perineum, vagina, large bowel
haematogenous: TB, Staph aureus