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Pharm 2 > UTI, STI > Flashcards

UTI, STI Flashcards

1
Q

symptom relief for dysuria

A

Phenazopyridine (Pyridium, Rx) (AZO OTC)

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2
Q

AEs: turns urine orange/red, false positive nitrites on UA, mild nausea

A

Phenazopyridine (Pyridium, Rx) (AZO OTC)

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3
Q

1st line for uncomplicated UTI

A

Nitrofurantoin 100mg PO BID x 5 days
Trimethoprim/sulfamethoxazole one PO BID x 3 days
Fosfomycin one 3g sachet powder orally once

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4
Q

AEs: GI, rare pulmonary fibrosis

A

nitrofurantoin

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5
Q

nitrofurantoin cautions

A

eldery, renal dysfunction

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6
Q

batrim contras

A

evere hepatic dysfunction, pregnancy, use w/ methotrexate

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7
Q

AEs:
* severe/fatal dermatologic rxns (SJS, TEN), discontinue at FIRSTS occurrence of skin
rash or any adverse rxn
* Hyperkalemia esp when on another medication that promotes retention of K+

A

bactrim

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8
Q

AEs: N/D, HA, renal dysfunction for multiple doses (no need for renal/hepatic dosign)

A

fosfomycin

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9
Q

fosfomycin for pyelonephritis?

A

no

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10
Q

1st line for enteroccoccal UTI

A

amoxicillin

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11
Q

major drug interaction for cipro

A

tizanidine

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12
Q

AEs: diarrhea, irritability/agitation/nervousness/excitability, may lower seizure threshold, QT
prolongation, tendinopathy or tendon rupture possible, c. diff risk, increased risk of aortic
aneurysm/dissection in those already at risk

A

FQs

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13
Q

pyelonephritis tx

A

Ciprofloxacin 500 mg BID x 7 days
§ Levofloxacin 750 mg QD x 5 days
§ TMP-SMX one double strength tablet BID x 14 days

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14
Q

1st line for UTI in pregnancy

A

amoxicillin / augmentin / cefpodoxime X 14 days

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15
Q

nitrofurantoin in men?

A

no

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16
Q

length of tx for male UTI

A

7-14 days

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17
Q

1st line for prostatitis

A

cipro, levo, bactrim 2-4 wks

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18
Q

HPVs that cause most cervical cancers

A

16 and 18

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19
Q

HPVs taht cause anogenital warts

A

6, 11

20
Q

what age to give HPV vax

A

11-12

21
Q

patient topical tx of genital warts not ok when?

A

> 5 warts, >1 cm

22
Q

indication: Podofilox solution or gel, Imiquimod, Veregen

A

genital warts

23
Q

Podofilox length of tx

A

Apply BID for 3 days, then 4 days off
§ Repeat cycle max 4 times until warts resolve (1 month)

24
Q

Imiquimod length of tx

A

max 4 months

25
Q

Sinecatechins (veregen) length of tx

A

max 4 months

26
Q

contra: Sinecatechins (veregen)

A

HIV, HSV

27
Q

counseling for topical genital warts tx

A

Cover warts w/ thin layer of medicine
§ Wash hands after use, do not get in eyes, nose, mouth
§ Avoid inside vagina, urethra, rectum
§ Do not occlude warts + medication w/ bandage but underwear/gauze is okay if irritated
§ Do not apply internally or to open wounds
§ May weaken condoms or diaphragms

28
Q

topical genital wart tx ok in pregnancy?

A

no

29
Q

Caustic acid that destroy the wart tissue via chemical coagulation

A

Trichloroacetic acid (TCA) 80-90%

30
Q

genital wart removal tx safe in pregnancy

A

TCA

31
Q

cuation for acyclovir, valacyclovir, famciclovir

A

renal failure

32
Q

counseling for acyclovir, valacyclovir

A

hydrate well to avoid cyrstal deposition in renal tubules

33
Q

when to start antiviral for HSV

A

asap after appearance of lesion and w/in 72 hrs

34
Q

length of tx for initial HSV

A

7-10 days

35
Q

condom use for how long after 1st HSV outbreak

A

12 months

36
Q

Most frequently reported bacterial STI

A

chlamydia

37
Q

test for chlamydia

A

NAAT on 1st catch urine OR vaginal swab

38
Q

chlamydia tx

A

doxy 100mg PO bid X 7 days OR azithromycin 1g PO OR levo 500mg PO QD X 7d

39
Q

most common presentation of gonorrhea

A

aysmptomatic

40
Q

gonorrhea tx

A

Ceftriaxone 500 mg IM in single dose for persons weighing <150kg (>150kg, 1 g ceftriaxone)

41
Q

any PO cephalosporins to treat gonorrhea?

A

no

42
Q

gonorrhea or chlamydia causes more severe PID?

A

gono

43
Q

cardinal presenting symptom of PID

A

lower abd pain, bilateral, <2 weeks

44
Q

inpatient tx for PID

A

cetriaxone + doxy + metronidazole

45
Q

trich tx

A

metronidazole 500mg PO bid X 7d

46
Q

AEs: unpleasant metallic taste, darkened urine, disulfiram-like reaction w/ alcohol
* Rare: reversible neutropenia, urticaria, rash, flushing, dry mouth

A

metronidazole

47
Q

syphillis tx

A

o 2.4 million units of Benzathine Penicillin G given IM once
§ Benzathine is stabilizer that releases penicillin slowly
o If neurosyphilis diagnosed, give dose weekly x 3

Pharm 2 (29 decks)

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