MS

Question 1

contras for Fingolimod (Gilenya®)

Answer 1

MI, unstable angina, stroke, TIAs, decompensated HF requiring hospitalization, class III/IV HF, h/o 2nd or 3rd degree AV block, sick sinus syndrome (unless has a pacemaker, baseline QTc > 500, or treatment with class Ia or III antiarrhythmic