UTI, Pulmonary infections, skin and soft tissue infections Flashcards

1
Q

What is Cystitis?

A

Bladder infection that causes inflammation of the bladder

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2
Q

What is Pyelonephritis?

A

Kidney infection

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3
Q

What is Urosepsis?

A

When a UTI spreads to the kidneys and causes sepsis

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4
Q

What is CAUTI?

A

Cather Associated UTI

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5
Q

what is the value indicating UTI in urine culture

A

10^5 CFU/ml (colony forming unit)
- 100,000

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6
Q

what does 10,000-100,000 CFU indicate

A

possible UTI, to check symptoms

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7
Q

what does <10,000 CFU indicate

A

likely contamination

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8
Q

❗list 8 gram -ve organism that cause UTI + which is the most common

A

e.coli: most common

klebsiella pneumonia

proteus: a/w kidney stones (staghorn calculas)

enterobacter, citrobacter, morganella, serratia

pseudomonas aeruginosa: (hospital bug) esp prev atbx exposure, presence of urinary catheter

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9
Q

❗list 1 gram positive organism that cause UTI

A

enterococcus
- usually in pt w abnormal anatomy or over exposure to atbx

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10
Q

❗list 1 fungus that cause UTI

A

candida
- usually due to recent atbx exposure

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11
Q

What is the treatment for Cystitis and CAUTI?

A

PO Antibiotics
- short treatment duration (3-7 days)

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12
Q

What is the treatment for pyelonephritis and Urosepsis

A
  • Start with IV antibiotics
  • Followed by PO antibiotic if improving after 48 hours
    • Total antibiotic duration - 7 to 14 days (Slightly longer)
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13
Q

What happens if patient has a ureteric stent or catheter and infection persists?

A

Remove foreign material and give antibiotics

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14
Q

Should antibiotics be given for asymptomatic UTI + why?

A

No, to prevent antibiotics resistance

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15
Q

what is the risk factor for asymptomatic UTI

A

> 65 y/o

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16
Q

Which patients should receive antibiotics for asymptomatic UTI? (5)

A
  • Pregnant women
    • To prevent lower to upper UTI
  • Pt undergoing urological procedure or surgery
    • To prevent sepsis due to additional foreign items inserting into urethra
  • Children with repeated UTI
  • Immunocompromised patients
  • Kidney transplant patients
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17
Q

which pt require long term atbx prophylaxis for UTI

A
  • children w recurrent UTI & vesicoureteral reflux w risk of renal scarring
  • pt w UTI that affects their QOL
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18
Q

❗what does candida in urine culture indicate

A

UTI due to over exposure of atbx

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19
Q

What does Susceptible, increased exposure mean in a C&S test

A

The bacterial strain causing the infection can be inhibited by the antibiotic tested, but higher concentrations of the drug than normal are required for effective treatment

20
Q

What are the 3 types of Pneumonia?

A
  • Community acquired pneumonia (CAP)
  • Hospital acquired pneumonia (HAP)
  • Ventilator associated pneumonia (VAP)
21
Q

Typical vs atypical bacteria?

A
  • Typical: Have characteristic shapes and susceptible to certain antibiotics
  • Atypical: Dont have gram stain color and have different characteristics
22
Q

❗Pathogens that causes CAP? (8)

A

typical: streptococcus pneumoniae, haemophilus influenzae

atypical: chlamydia pneumoniae, mycoplasma pneumoniae, legionella pneumophila

others: staph aureus (post influenza), kleb pneumoniae, influenza (virus)

23
Q

❗Pathogens that causes HAP/VAP? (6)

A
  1. strep pneumoniae
  2. haemophilus influenzae
  3. ‘coliforms’
    eg. e coli, klebsiella, enterobacter
  4. pseudomonas aeruginosa
  5. acinetobacter
  6. MRSA
24
Q

What is the test and sample for bacterial pneumonia?

A

test: microscopy (gram stain), culture & sensitivity

samples: sputum, endotracheal aspirate (ETA), bronchioalveolar lavage (BAL)

25
❗what does high epithelial cells indicate in gram stain for pneumonia
poorly taken sample
26
What is the test and sample for viral pneumonia?
test: PCR samples: sputum endotracheal aspirate (ETA) bronchioalveolar lavage (BAL)
27
Which 2 organism can be expected in urine antigen test (POCT) for pneumonia
- strep pneumoniae - faster to grow but beware of false positive result - legionella pneumophila - difficult & take time to grow
28
For atypical CAP, which test should be done
PCR: Undetectable by gram stain as they lack cell wall
29
When do we take blood cultures?
When patient is febrile or septic
30
Why is Bronchio-alveolar Lavage (BAL) more accurate than sputum
because it is more invasive, usually done in sedated/ICU pts - not sterile, but clean specimen
31
Signs of cellulitis?
E.g. Red, hot, tender leg
32
Signs of impetigo?
- Bacterial skin infection - Honey colored, crusted lesions around peri-oral regions
33
Signs of intertrigo?
Uncomfortable sticky redness under breast folds
34
Signs of lymphangitis?
Tender track along lymphatic vessels
35
Which two organisms is responsible for acute soft tissue infection?
- staph aureus - eg. MSSA, MRSA - beta haemolytic strep (esp group A strep)
36
What is the treatment for acute soft tissue infection
Antibiotics
37
What is the bug responsible for lymphangitis?
Group A strep
38
list 2 bug that is responsible for type 2 necrotising facsciitis (NF) + which is the classical bug
- group A strep: classical bug - staph aureus
39
What is the bug responsible for both gas gangrene and nec fas?
Clostridium perfringens
40
How should we sample nec fas or gas gangrene?
- Skin/flesh sample - Dont bother sending swabs
41
When should you send swab samples and when you should not?
- Swab pus, liquids and wounds that can provide wet samples - Dont bother swabbing intact skins as u may just pick up skin flora
42
what are the cause of chronic wound (2)
- gram negative organism - gram negative + gram positive organism
43
for diabetic wound ulcer, what is the steps to obtain the sample
- clean the wound - obtain deep sample - do not take superficial wound sample
44
Definition of Septic arthritis
Infection of joint: Knee or hip
45
Definition of Osteomyelitis?
Infection of the bone
46
Definition of Discitis?
Infection of the spine