UTI and Pyelonephritis Flashcards
What do the kidneys do?
-filters waste products from the blood -maintains fluid, electrolyte and acid/base balance -excretes metabolic waste products -BP -erythropoiesis -bone mineral density
What does the lower urinary tract do?
stores urine and empties the bladder
Bacteria that causes UTI
gram negative: -escherichia coli or species of Klebsiella -Staphylococcus -Proteus, Pseudomonas, or Enterobacter
Infections of lower UTI?
-Cystitis (inflammation of bladder) -Prostatitis (infection of prostate) -Urethritis (infection of urethra)
Infections of upper UTI?
-Acute pyelonephritis (infection of kidneys; UTI makes its way up to kidneys) -Chronic pyelonephritis -Renal abscess -Interstitial nephritis -Perirenal abscess
Uncomplicated UTI?
-normal UTI -acquired in community -more common in women (urethra is shorter)
Complicated UTI?
-acquired in hospital (nosocomial) -some kind of urological abnormality/something else in urinary tract going on -pregnancy with UTI = complicated -diabetic causes complications cause there is sugar in the urine and bacteria likes sugar -recurrent UTI (3-4/year)
Pathophysiology of Infections of the Urinary tract?
-washout- urine cleans out urinary tract there is a lining in the urinary tract that protects it from microbes -IGA- immunoglobin which protects from microbes ureter has peristaltic waves which moves bacteria away from kidneys and out of the body normal flora -in men- fluid secreted from the prostate protects from microorganisms
Routes of Infection?
-Ascending infection: related to instrumentation like catheter’s -Hematogenic: spread through blood -direct extension: infection spreads to adjacent organs
Ascending Route of Bacterial Invasion goes where?
to the kidneys (urine reflux into kidneys)
major Predisposing Factors for Infection of the Urinary Tract?
-age (older) -gender (women) -obstruction to flow of urine -pregnancy -narrowing of urethra -kidney stones -urinary stasis (immobile, narcotics) -immunosuppression -diabetes
Predisposing Factors for Infection of the Urinary Tract in the Elderly?
- higher incidence of chronic illness 2. presence of infected pressure ulcers 3. immobility with incomplete bladder emptying 4. use of bedpans rather than commodes 5. persistent use of antimicrobial agents
Clinical Manifestations of Lower UTI are related to difficulty with?
storage of urine -difficulty storing larger amount of urine in bladder -urgency of needing to pee due to less storage space -incontinent or nocturnal incontinence or difficulty emptying bladder -burning/pain -dribbling (at end of voiding) -weak stream of urine -may not be able to void at all -hesitancy voiding -intermittent (stopping and starting while urinating)
Clinical Manifestations of UTI?
-Suprapubic/Pelvic Pain -hematuria -sediments in urine -strong foul odor -fever + chills (sometimes but more common in infection of kidney)
Clinical Manifestations of Lower UTI in the Elderly?
-cognitive impairment (confusion/changes in LOC) -low-grade/no fever/below normal temperature -vague pain -fatigue/malaise feeling -anorexia -new incontinence