UTI

Question 1

Staph Sapro

Answer 1

Risk factors= recent sexual activity and bacteremia less than 10 to the fifth leads to Acute Urethral syndrome
Catalase +, Coagulase -, gamma hemolytic
Facultative anaerobe and novobiocin resistant

Question 2

Klebsiella Pneumonia

Answer 2

Causes cystitis and pyelonephritis
Gram neg rod, thick LPS capsule, lactose fermentor, Indole neg
Difficult to tx: R plasmids and chromosomal genes
Fecal contamination of cath

Question 3

Uropathogenic E Coli

Answer 3

Causes Cyst and pyelo
Gram neg rod, VFs: Fimbrae, flagella, capsule, siderphores, adhesins, sialic acid for invasion, endotoxin (LPS)
Indole +, beta-hemolytic, lactose ferm, oxidase -

Question 4

Enterococcus Faecalis

Answer 4

Causes cyst and pyelo via cath
Gram pos cocci
Nitrite -, catalase -, Bile ENT +, LAncefield (PYR) group D, facultative anaerobe
Resistant to multi anti gram pos drugs so need 10xMFC

Question 5

Psudomonas Aeruginosa

Answer 5

Causes cyst and Pyelo
Gram neg rod, exotoxin A (blocks EF2 via ADP ribosylation inhib protein synth), some capsule, biofilms, obligate aerobe
oxidase +, lactose nonferm, indole -
Transmission via soil/water/aerosols (CF pts)
Tx: combo due to efflux pumps

Question 6

Proteus Spp

Answer 6

Causes cyst and pyelo via cath
Gram neg rod, urease, flagella, endotoxin (LPS)
Indole -, lactose nonferm, oxidase -
Complication= struvite crystals, staghorn calculi

Question 7

BK virus

Answer 7

Urethral stenosis and nephropathy
dsDNA virus, no envelope, latency in lymphocytes with decoy cells
Immunocomp=risk