uterine cancers Flashcards
the majority of endometrial cancers are ?
adenocarcinoma
two types of adenocarcinoma of endometrium are? ans most common of the two
type 1 - endometriod(most common 80%) and type 2- serous and clear cell
precursor lesions of type 1 and 2 endometrial adenocarcinoma are respectively
type 1 - atypical hyperplasia
type 2 - endometrial intraepithelial carcinoma
an endometrial thickness of what is suspicious of cancer in post menopausal women ( pre- meno?)
> 4mm (>16mm in pre menopause)
what would be your initial investigations in suspected endometrial cancer? and treatment
PV+ speculum TV ultrasound - measure endometrial thickness endometrial biopsy dilatation and curettage (under GA) hysterectomy
when are atypical and typical hyperplasia seen and what are treatments for each
typical - anovulatory teens and perimenopausal - treat w/ mirena
atypical- seen before carcinoma treat with hysterectomy
what type of endometrial cancer is associated with lynch syndrome ?
endometroid
different types of endometrial cancer
adenocarcinoma
endometrial sarcoma
carcinosarcoma
leiomyosarcoma
mainstay of treatment in endometrial cancer?
hysterectomy with bilateral salpingo-oopherectomy (usually laparoscopic) - lymphadenoathy may be advised
recurrence od endometrial cancer mostly seen ?
in vagina
staging system used ?
FIGO
wha type of endometrial carcinoma is associated with uunopposed oestrogen
type 1 - endometriod