usmlerx peds 1 Flashcards
Crigler Najjar Syndrome
Unconjugated Hyperbilirubinemia
Black pigmented liver
Dubin Johnson
Tx: NEC
Breast Milk
Musty body odor
PKU
FTT, Persistant Jaundice, poor feeding
Classic Galactosemia (avoid galactose and lactose)
Exchange Transfusions for Jaundice
Neurotoxicity is present or bili levels are insanely high
Sx: Wilm’s Tumor
Flank mass not crossing midline n/v Anemia, HTN Hematuria WAGR
WAGR
WAGR Wilms tumor Aniridia GU abnormalities Retardation
Sx: ARPKD
BILATERAL masses Pulm Hypoplasia Oligohydramnios HTN
Three per second spike and wave discharges
Absence Seizures (Tx: Ethosuximide)
Tx: Complex Partial Seizure
carbam, oxcarb, lamotrig, phenytoin, topiramate, valproic acid
Loss of consciousness looking upward
Arnold Chiari
Arnold Chiari presents
usually in adulthood
Dandy Walker presents
early infancy
Sx: Dandy Walker
(4th ventricle enlargement) Motor- jerky mvmnts ICP Convulsions, vomiting Eyes- mvmnts
Sx: SCIDs
small thymus FTT Diarrhea Recurrent infxns
What is Transposition of the Great Vessels?
Aorta stems from RV Pulm artery stems from LV -MCC of Cyanotic Congenital HD
Egg shaped heart
Transposition of Great Vessels
Tx: TGV
Prostaglandin E1s OR Balloon Atrial septostomy to open/maintain ASD until surgiery to switch the vessels
Sx: Malathion poisoning
Organphosphate (incACh)-> DUMBBELS Diarrhea, Urination, Miosis, Bronchconstriction, Bradycardia, Emesis, Lacrimation, Salivation
Sx: Anticholinergic poisoning
Blind as a bat (Myadriasis) Mad as a Hatter Red as a Beet Hot as a Hare Dry as a Bone Bladder/Bowels lose their tone and the heart runs alone
Child with cold, RUQ Pain
Acetaminophen overdose
Sx: Ethylene Glycol overdose
Ataxia/Confusion HTN, Tachypnea, Tachycardic *Oxalic acid crystals in urine Kussmaul, incAG metabolic acidosis
Tx: Ethylene Glycol
Fomepizole or Ethanol (direct competitor for Alc Dehyd’ase)
Dx: Bacterial Vaginosis
Wet mount prep showing Clue cells
Sx: Lower UTI vs. Upper UTI
Flank pain, fever, chills indicate upper UTI (ie Pyelonephritis)
Tx: Rickettsia
Doxycycline
Maculopapular pink rash starting on trunk and spreads to face and hands, fever
Roseola
Tx: Roseola (Sixth Dz)
None, self limiting
Etiology: Scarlet Fever
Group A Strep (S. Pyogenes)
Sx: Scarlet Fever
Strawberry tongue Sandpaper like rash on trunk that desquamates
Scarlet Fever leads to
Rheumatic Fever
Tx: Scarlet Fever
Penicillin
Hypokalemia, HTN, Ambiguous Genitalia
11-?-OH Deficiency (So the kid gets increased amounts of Sex androgens and also 11 Deoxycort’s which yield the HTN)
Sx: Sickle Cell
Anemia Pallor, Fatigue even kids can have strokes!!
Murmur loudest at L Sternal Border, nonbounding pulses
TGV
Murmur loudest at L Sternal Border, bounding pulses
Truncus Arteriosus
Rash on Flexor surfaces (elbow, buttocks, knees)
Atopic Dermatitis “Flexzema”
Raised red lesions with silvery scales
Psoriasis
Vaccinations and acute illnesses
Fever is not a contraindication but it can be cause to delay. Fever + URI + Otitis Media would be cause to give antibiotics and delay vaccination
Dapsone treats
Leprosy ITP Prophylaxis for HIV Jiroveci
Tx: Systemic mycoses
Amphotericin B or Fluconazole
Tx: CMV
Foscarnet
Tx: Varicella Zoster
Acyclovir
Tx: EBV
Acyclovir
Sx: Trisomy 13
Microcephaly, Microphthalmia Polydactyl Holoprosencephaly
Sx: Trisomy 18
Horseshoe kidneys Micrognathia Congenital Heart Defects Malrotation of GI
Sx: RSV
Hypersecretions lead to mucus plugs which leads to hyperinflation Ronchi/Wheezing Rinorrhea
Sx: Roseola
High Fever Rash
Complications of Supracondylar Humerus Fractures
Compartment Syndrome (dt Brachial a.) Volkmann’s Contracture (ischemic contracture shortening of the forearm muscles)
Lisch Nodules
Raised pigmented hamartomas of the iris in NF-1
Retinal Hamartomas
Tuberous Sclerosis
Leukocoria
Retinoblastoma
Pediatric Glaucoma
Sturge Weber (50%)
Nonretinal Hamartomas
Tuberous Sclerosis
Sx: Pertussis
Inspiratory stridor (“whoop”) Cough, Coryza Low grade fever Paroxysmal coughing
Sx: H Influ
Kids- Hi fever, Myalgia, Cough, Chills Babies- URI, Bronchitis, Bronchiolitis, pneumonia, laryngeotracheitis, myositis, parotitis
Sx: Polio
Fever, Malaise Pharyngitis n/v weak skeletal/cranial muscles, flaccid paralysis
Sx: Measles
Cough Coryza Conjunctivitis Koplik’s spots
Koplik’s Spots Appearance
small red spots with grey centers on buccosal mucosa
Legg Calve Perthes Disease
Proximal Femur Epiphysis vascular osteonecrosis ~4-8yoa
Slipped Capital Femoral Epiphysis
Salter Harris type 1 Fx of the proximal femoral epiphysis -11-15yoa (often African American boys)
Sx: Transient Tachypnea of the Newborn
Respiratory Distress (cyanosis, nasal flaring etc) Fissures, prominent pulm vascular markings Overexpansion of lungs/Flattened diaphragm
Sx: Diaphragmatic Hernia
Air filled bowel in chest Decreased breath sounds over hernia Displaced Heart sounds to opposite side of hernia
Sx: Neonatal Respiratory Distress Syndrome
fine reticular granular pattern and air bronchograms pre-term
Sx: Pulmonary Hemorrhage
Diffuse Opacified Lung(s), air bronchogram
Sx: Pulm Interstitial Emphysema
Linear lucencies radiating from the hilum, or cystlike blebs <48hrs of birth HoTN, Bradycardia, Hypoxic Preterms
Risk Factors: Transient Tachypnea of the Newborn
Premature birth Precipitous birth Cesarean Section
Dx: Tinea Pedis
KOH prep (see branching hyphae)
Dx: Tinea Capitis
Wood’s lamp
Dx: Porphyria Cutanea Tarda
Wood’s lamp
G+ cocci in clusters, bacterial tracheitis, brassy cough, hi fever in kids
S. Aureus
G- Diplococc, bacterial tracheitis, kids
Moraxella Catarrhis
G- Rod, bacterial tracheitis, kids
H Influ (nontypeable)
Sx: Congenital Adrenal Hyperplasia, 21-OH Deficiency
Deficiency of Aldosterone and Cortisol (Inc ACTH) Inc Sex Hormones leads to virilized genitalia
Sx: Nonbilious vomiting, RUQ mass
Pyloric Stenosis
Hypochloremic Metabolic Alkalosis
Pyloric Stenosis
Double bubble sign
Malrotation
Bilious vomiting with bloody stools
Volvulus
RUQ olive mass, nonbilious vomiting
Pyloric Stenosis
Sausage mass with currant jelly stools
Intussusception
Malrotations are associated with
Diaphragmatic hernias Gastroschisis Omphalocele Intestinal Atresia
Sx: Volvulus
Bilious vomiting Bloody stool/Melena Ligament of Treitz on right side Duodenal “Beak”
Sx: Rotavirus
Nonbloody diarrhea fecal oral spread Dehydration Vomiting Low-moderate fever
daycare center, january, diarrhea
Rotavirus
Sx: Salmonella
n/v diarrhea (may contain blood or mucus)
reptile contact, diarrhea
Salmonella
Antibiotics should never be prescribed for which diarrhea
Salmonella
G- Flagellated rod
Campylobacter jejuni
Sx: Campylobacter
Fever HA Bloody Diarrhea
Sx: C. Difficile
Fever Diarrhea (test stool for C-D toxins)
Sx: Enteric Adenovirus
Diarrhea URI-like symptoms Spring/summer
Sx: Giardia
Watery diarrhea Flatulence Foul smelling greasy stools
Sx: Shigella
Fever Bloody, pus speckled diarrhea Fecal-oral, daycares
Sx: S. Aureus diarrhea
Emesis is often first symptom Right after food
Sx: Vibrio
Watery diarrhea (rice water) seafood
Vibrio Cholera vs Parahaemolyticus
Parahem- Japan, no Tx, Resolves in 3 days
Tx: Vibrio
Fluids -can also give Doxy or Flouroquinolone
Tx: Shigella
Flouroquinolones
Sx: E. Coli- Enterotoxigenic
rice water stool in 3rd world travelers
Sx: E. Coli- Enterohemorrhagic
Hemorrhagic colitis, O157:H7- HUS syndrome
Sx: E. Coli- Enteroinvasive
Fever WBCs in stool
Sx: HUS
Thrombocytopenia Renal Failure (Uremia) Hemolytic Anemia
Sx: Angelman
angeLMAM’S Laughing Mental delays Ataxia/mvmnt disorders Microcephaly Seizures (tonic clonic)
Sx: Epiglottitis
Rapid fever Dysphagia Drooling Lung sounds, cyanosis “Sniffing position” (next extension)
MCC of Epiglottitis
(Used to be Hib before vaccine) nontype H Influ, Streps, virals
Oily stools, jaundice
CF
Pancreatitis, Hypoproteinemia, Lung sounds
CF
Small hard nodule on testicle, gynecomastia
Choriocarcinoma (B-hcg yields gynecomastia)
Testicle tumors with ?fp
Teratomas Teratocarcinomas Embryonal Cell tumors
Urinary Catecholamines in a child
Neuroblastoma
Sx: Neuroblastoma
Periorbital bruising, Proptosis Lymphadenopathy HTN
Sx: ALL
Pancytopenia Lymphadenopathy Fever FTT Petechiae (NOT bruising), Pallor
Worst prognostic feature of Aortic Stenosis
Dyspnea
Hydrops Fetalis
Congenital Syphilis
Cutaneous Lesions on hands/soles of neonate
Congenital Syphilis
Sx: Congenital Syphilis
Hepatosplenomegaly, Jaundice Frontal Bossing, Short Maxilla, Hi Palatal Arch Hutchinson’s triad Saddle Nose Perioral Fissure
Metaphyseal Dystrophy and Periostitis
Congenital Syphilis
Hutchinson’s Triad
Blunted upper incisors Interstitial Keratitis Eighth Nerve Deafness (Congenital Syphilis)
G- Intracellular Aerobe
C. Trachomatis
Sx: DiGeorge
Cleft palate Abnormal facies Thymic aplasia Cardiac (Tetralogy) Hypocalcemia/parathyroid hypoplasia
Dx: Sickle Cell
Hemoglobin Electrophoresis
Dx: Chronic Granulomatous Disease
Nitroblue Tetrazolium
Dx: VACTERL
Renal ultrasound
VACTERL
Vertebrae, Anal atresia, CV tree, Tracheo-Esophageal fistula, Renal
Rocky mountain rash
starts on hands and feet and spreads to trunk
Sx: Rh Incompatability
MUST have had kids before! Mother- Rh- Unconjugated hyperbilirubinemia Anemia inc Hematopoeiesis Coombs
Breast Jaundice is usually seen at Day
Day 3
Tx: Mild Persistant Asthma
Lo Dose Inhaled Corticosteroid
Cromolyn Sodium is
block Leukotriene Rec ->block Mast cell Asthma Prophylaxis (has to be started weeks ahead of time)
Tx: Moderate Persistant Asthma
Short acting bronchodilators low to medium dose corticosteroids Long acting inhaled B2 agonist