USMLE Step 1 First Aid - Key Associations Flashcards
Give the most common/important Association for each Disease/Finding
Disease/finding: Actinic (solar) keratosis
Most common/important associations: Squamous cell carcinoma
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Disease/finding: Acute gastric ulcer associated w/ CNS injury
Most common/important associations: Cushing’s ulcer (increased ICP stimulates gastric secretion)
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Disease/finding: Acute gastric ulcer associated w/ severe burns
Most common/important associations: Curling’s ulcer (greatly reduced plasma volume results in sloughing of gastric mucosa)
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Disease/finding: Alternating areas of transmural inflammation and normal colon
Most common/important associations: Skip lesions (Crohn’s disease: autoimmune)
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Disease/finding: Aneurysm, dissecting
Most common/important associations: HTN
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Disease/finding: Aortic aneurysm, abdominal and descending aorta
Most common/important associations: Atherosclerosis
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Disease/finding: Aortic aneurysm, ascending
Most common/important associations: Tertiary syphilis
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Disease/finding: Atrophy of the mammillary bodies
Most common/important associations:
Wernicke’s encephalopathy (the Triad symptoms of ataxia, ophthalmoplegia, and confusion), caused by thiamine deficiency
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Disease/finding: Autosplenectomy (fibrosis and shrinkage)
Most common/important associations: Sickle cell anemia (HbS)
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Disease/finding: Bacteremia/pneumonia (IV drug user)
Most common/important associations: S. aureus
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Disease/finding: Bacteria associated w/ stomach cancer
Most common/important associations: H. pylori
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Disease/finding: Bacterial meningitis (adults and elderly)
Most common/important associations: Streptococcus pneumoniae
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Disease/finding: Bacterial meningitis (newborns and kids)
Most common/important associations: Group B streptococcus (newborns), S. pneumoniae/Neisseria meningitidis (kids)
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Disease/finding: Benign melanocytic nevus
Most common/important associations: Spitz nevus (most common in first two decades)
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Disease/finding: Bleeding disorder w/ GpIb deficiency
Most common/important associations: Bernard-Soulier dz (defect in platelet adhesion)
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Disease/finding: Brain tumor (adults)
Most common/important associations: Supratentorial: mets < astrocytoma (including glioblastoma multiforme) < meningioma < schwannoma
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Disease/finding: Brain tumor (kids)
Most common/important associations:
Infratentorial: medulloblastoma (cerebellum) or
supratentorial: craniopharyngioma (cerebrum)
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Disease/finding: Breast cancer
Most common/important associations: Infiltrating ductal carcinoma (in USA, 1 in 9 women will develop breast cancer)
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Disease/finding: Breast mass
Most common/important associations: 1.) Fibrocystic change 2.) Carcinoma (in postmenopausal women)
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Disease/finding: Breast tumor (benign)
Most common/important associations: Fibroadenoma
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Disease/finding: Bug in debilitated, hospitalized pneumonia patient
Most common/important associations: Klebsiella
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Disease/finding: Cardiac primary tumor (kids)
Most common/important associations: Rhabdomyoma
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Disease/finding: Cardiac manifestation of lupus
Most common/important associations: Libman-Sacks endocarditis (nonbacterial, affecting mitral)
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Disease/finding: Cardiac tumor (adults)
Most common/important associations: 1.) metastasis 2.) Primary myxoma (4:1 Left to right atrium; “ball and valve”)
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Disease/finding: Cardiomyopathy
Most common/important associations: Dilated cardiomyopathy (40% are familial)
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Disease/finding: Cerebellar tonsillar herniation
Most common/important associations: Arnold-Chiari malformation (often causes hydrocephalus)
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Disease/finding: Chronic arrhythmia
Most common/important associations: Atrial fibrillation (associated w/ high risk of emboli)
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Disease/finding: Chronic atrophic gastritis (the autoimmune version of the dz)
Most common/important associations: Predisposition to gastric carcinoma (can also cause pernicious anemia)
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Disease/finding: Clear cell adenocarcinoma of the vagina
Most common/important associations: DES exposure in utero
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Disease/finding: Congenital adrenal hyperplasia
Most common/important associations: 21-hydroxylase deficiency
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Disease/finding: Congenital cardiac anomaly
Most common/important associations: VSD
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Disease/finding: Congenital conjugated hyperbilirubinemia (black liver)
Most common/important associations: Dubin-Johnson syndrome (inability of hepatocytes to secrete conjugated bilirubin into bile)
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Disease/finding: Constrictive pericarditis in developing world
Most common/important associations: Tuberculosis
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Disease/finding: Coronary artery involved in thrombosis
Most common/important associations: LAD < RCA < LCA
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Disease/finding: Cretinism
Most common/important associations: Iodine deficit/hypothyroidism
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Disease/finding: Cushing’s syndrome
Most common/important associations: 1.) Corticosteroid therapy 2.) Excess ACTH secretion by pituitary
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Disease/finding: Cyanosis (early; less common)
Most common/important associations: Tetralogy of Fallot, transposition of the great vessels, truncus arteriosus
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Disease/finding: Cyanosis (late; more common)
Most common/important associations: VSD, ASD, PDA
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Disease/finding: Death in CML
Most common/important associations: Blast crisis
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Disease/finding: Death in SLE
Most common/important associations: Lupus nephropathy
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Disease/finding: Dementia
Most common/important associations: 1.) Alzheimer’s disease 2.) Multiple infarcts
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Disease/finding: Demyelinating disease
Most common/important associations: Multiple sclerosis
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Disease/finding: DIC
Most common/important associations: Gram-negative sepsis, obstetric complications, cancer, burn trauma
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Disease/finding: Dietary deficit
Most common/important associations: Iron
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Disease/finding: Diverticulum in pharynx
Most common/important associations: Zenker’s diverticulum (diagnosed by barium swallow)
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Disease/finding: Ejection click
Most common/important associations: Aortic/pulmonic stenosis
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Disease/finding: Esophageal cancer
Most common/important associations: Squamous cell carcinoma
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Disease/finding: Food poisoning
Most common/important associations: S. aureus
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Disease/finding: Gene involved in cancer
Most common/important associations: p53 tumor suppressor gene
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Disease/finding: Glomerulonephritis (adults)
Most common/important associations: Berger’s disease (IgA nephropathy)
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Disease/finding: Gynecologic malignancy
Most common/important associations: Endometrial carcinoma
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Disease/finding: Heart murmur
Most common/important associations: Mitral valve prolapse
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Disease/finding: Heart valves involved in bacterial endocarditis
Most common/important associations:
Mitral (rheumatic fever)
Tricuspid (IV drug abuse)
Aortic (2nd affected in rheumatic fever)
Give the most common/important Association for each Disease/Finding
Disease/finding: Helminth infxn (in USA)
Most common/important associations:
- ) Enterobius vermicularis
- ) Ascaris lumbricoides
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Disease/finding: Hematoma - epidural
Most common/important associations: Rupture of middle meningeal artery (arterial bleeding is fast)