USMLE Other Flashcards
Acute angle closure glaucoma / Symptoms and presentations
pain, diminished visual acuity, seeing halos around lights, a red eye, headache, and a dilated pupil.
Alcoholic hepatitis
Maddrey’s Discriminant function score:
Treatment / how long?
modified Maddrey’s discriminant function score > 32 or hepatic encephalopathy should be considered for treatment with prednisolone 40 mg daily for four weeks followed by a taper.
Alzheimer disease
Effects in daily living and instrumental activities of daily living; other language difficulties; or personality changes. MMSE scores of 19 to 24 suggest mild dementia, and scores of 10 to 19 suggest moderate dementia.
When to order ankle radiographs
Ankle radiographs should be obtained only
- When patients are unable to bear weight
- Who have bony tenderness to palpation at the posterior edge of either the lateral or medial malleoli.
Anti Depressant therapy / Therapy time periods
Remission
post remission therapy
The goal of treatment / remission within 6 to 12 weeks / continue treatment for 4 to 9 months thereafter.
Patients assessed 2-4 weeks after starting therapy for adherence and again at 6-8 weeks for response to therapy. Using a formal tool for severity assessment (such as the PHQ-9) helps quantify the nature of the response; patients are considered to have at least a partial response if a 50% or greater decrease in symptom score has occurred.
Benign paroxysmal positional vertigo (BPPV).
- Otolith repositioning, commonly known as the Epley maneuver
- Tinnitus, ear pain, and hearing loss are absent, and nausea that is sufficiently severe or prolonged to cause vomiting is rare.
Causes of rhinitis
- Non allergic
- Allergic
- Occupational
- Rhinitis medicamentosa
- Pregnancy
- Systemic Dz
- Medications
- Vasomotor and Gustatory
- Seasonal, perennia
- Animal handles, food processors
- Cocaine, regular nasal decongestants
- Unclear
- Hypothyroid, Wegeners, sarcoid
- Oral Contraceptives, sildenafil, Clonidine
Central retinal artery occlusion / CRAO / Symptoms & presentation
visual acuity is markedly diminished in the affected eye to either finger counting or light perception. There is an afferent pupillary defect. On funduscopic examination, the retina appears pale, either segmentally or completely.
Central vertigo
- Vertical nystagmus occurs immediately with the Dix-Hallpike maneuver.
- MRI with angiography of the brain.
- Prolonged (>1 min), and nonfatigable
- Due to ischemia or infarct in the brainstem or cerebellum.
Child-Turcotte-Pugh class and postoperative mortality
Patients with CTP class / scores have postoperative mortality
A (0-6 points) 10%
class B (7-9 points) 30%
class C (≥10 points) 80%
Dantrolene
Hyperthermia associate with neutroleptic syndrome
Tx: Neuroleptic malignant syndrome - Lorazepam and IVF
Nonasthmatic eosinophilic bronchitis
patients with chronic, nonproductive cough without an apparent cause, including asthma; sputum examination for eosinophils is useful in establishing the diagnosis.
Essential Mixed Cryoglobulinemia
Associated with what dz?
- Hep C
- palpable purpura
- Arthalgias
- Renal Dz (MPGN)
- purpuric skin lesions in LE progress to necrosis
Fenofibrate
- Reducing serum triglyceride levels, with observed decreases of 20% to 50%.
GAD Tx?
CBT or SSRI/SNRI
Herbal meds
- Ginko Biloba
- Ginseng
- Saw Palmetto
- Black cohosh
What are they used for ?
What is thier side effect?
- Ginko Biloba : Memory enhan
- Ginseng: mental performance
- Saw Palmetto: BPH
- Black Cohosh: Post manopausal
All increase chance of bleeding
Got Foot problems
- Charcot Joint
- Matatarsal stress fracture
- Morton’s neuroma
- Plantar fasciitis
- Progressive degenerative joint ds due to peripheral neuropathy / swelling, erythema and loss of sensation new the involved joint.
- In runners due to repetitive stress injury / after two weeks visible on Xray focal point tnederness near the metatarsal shaft.
- Interdigit nerve compression resulting in enlargement of planatal digital nerve - burning sensation and numbness usually between 3 and 4 metatarsals
- heel pain usually early mornings involves the plantar areas
Guttate psoriasis
- Varieant of psoriasis that occurs 2-3 weeks after a streptococcal infection
- Sole palms usually spared
Heavy menstrual bleeding - Treament outpatient
Severe/acute bleed
- Oral medroxyprogesterone acetate
- patient were orthostatic or dizzy from blood loss, intravenous estrogen would be appropriate. Parenteral conjugated estrogens are approximately 70% effective in stopping the bleeding entirely. Pulmonary embolism and venous thrombosis are complications of intravenous estrogen therapy.
Hereditary Angioedema
- Clinical Features
- Screening
- Tx
Clinical Features
- Angioedema without any urticaria or pruritus > 12 hrs
Screening (1 week after ffp treatment)
- C4 levels (C1 substrate)
- C1 inhibitor antigenic levels
- C1 inhib. functional levels
Tx:
- 1st line:
- C1 inhibitor / icatibant (bradykinin) / Ecallantide
- FFP
Prophylaxis
- Angdrogens (Danazol)
human papillomavirus vaccine
- Females between the ages of 11 and 26 years
- Males between the ages of 11 and 21 years.
Hyperlipidemia in pregnancy
- Colesevelam / Bile acid sequestrants are the best option
- STatins / Ezetimibe catagory X
- Gemfibrozil category C
IgG4 Related systemic dz
should be suspected in pt with the follwoing?
- Idiopathic pancreatitis
- Sclerosing cholangitis
- B/L salvary or lacrimal gland Enlargment
Dx
- IgG4 +ve plasma cells
- Peripheral eosinophilia
Tx
- Steriods
Licorice
- Stomach ulcers
- Hyperkalemia/HtN
Likelihood Ratio
Positive
Negative
LR + = Sensitivity / (1-specificity)
LR - = (1-Sensitivity)/ Specificity
Malitonin
Used when corssing 4 time zones for sleep
Manage advanced cancer pain
1-3 Mild
4-6 Moderate
7-10 Severe
The World Health Organization analgesic ladder
- ASA, acetaminophen, or NSAIDs mild pain (1-3).
- oxycodone and acetaminophen (combo pills) Moderate pain (pain score 4-6) / daily cumulative acetaminophen dose (
- Severe pain (pain score 7-10) is mainly treated with opioids.
Adjunctive therapies (antidepressants, anticonvulsants, corticosteroids, muscle relaxants) can be used at all levels of the analgesic ladder.
Indications for specialized RBCs Treatments
- W Ashed
- I RRADIATED
- L EUKOREDUCED
Irradiated: Immune / BMT
- BMT reciepients
- Acquired or congenital cellular immunodef
- blood donated by first or second degree relative
LeukoreduCed:
- Chronically transfused pt
- CMV seronegative at risk
- potenstial transplant pt
WAshed
- IgA def
- Complement dependent autoimmune hemolytic
- Allergic reaction to RBC
Manage chronic fatigue syndrome
- Graded exercise programs
- Cognitive-behavioral therapy
- 6 months - least four of the following symptoms:
- subjective memory impairment
- sore throat
- tender lymph nodes
- muscle or joint pain
- headache
- unrefreshing sleep
- postexertional malaise lasting longer than 24 hours.
Medications for Bulimia vs Anorexia
Bulimia : SSRI
Anorexia: Olanzapine
Bupropion is CI in eating disorders
Medications for Rhinorrhea vs Chronic Sinusitis
Ipratropium nasal spray for rhinorrhea
Chronic Sinusitis > 12 weeks NS Nasal spray
Metabolic syndrome:
Waist size
Dyslipidemia TAG
Dyslipidemia HDL
Blood pressure
Fasting glucose
At Least 3 of the following:
- Central obesity: waist circumference ≥ 102 cm or 40 inches (male), ≥ 88 cm or 35 inches(female)
- Dyslipidemia: TG ≥ 1.7 mmol/L (150 mg/dl)
- Dyslipidemia: HDL-C < 40 mg/dL (male), < 50 mg/dL (female)
- Blood pressure ≥ 130/85 mmHg
- Fasting plasma glucose ≥ 6.1 mmol/L (110 mg/dl)
Mild cognitive impairment
have a single or few areas of cognitive impairment, and the Mini-Mental State Examination score is typically 24 or 25.