Uses of tumor markers Flashcards

1
Q

adrenal carcinoma

A

steroids, catecholamines
serology
diagnosis

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2
Q

breast

A

CA 15-3, CA 27.29
serology/tissue IHC
monitoring recurrence

ER, PR, Her-2-neu
tissue IHC
response to therapy

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3
Q

carcinoid

A

5-HIAA
serology/urine
diagnosis

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4
Q

colorectal, stomach, pancreas

A

CEA, CA 19-9
serology/tissue IHC
prognosis, monitoring

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5
Q

choriocarcinoma

A

beta-HCG
serology, tissue IHC
diagnosis, prognosis, monitoring

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6
Q

germ cell tumors

A

AFP, B-HCG
serology, tissue IHC
diagnosis, prognosis, monitoring

LDH, PLAP (seminoma)
serology
prognosis, monitoring

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7
Q

hepatoma

A

AFP
serology/ tissue IHC
screening, diagnosis, prognosis, monitoring

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8
Q

lymphoma

A

LDH
serology
diagnosis prognosis

cytogenetic alteration
genetic analysis
diagnosis

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9
Q

melanoma

A

tyrosinase
serology
diagnosis

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10
Q

myeloma

A

immunoglobulins
serology
diagnosis, prognosis

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11
Q

ovarian

A

CA 125
serology, tissue IHC
diagnosis, monitoring recurrence

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12
Q

prostate

A

PSA
serology/tissue IHC
screening, diagnosis, prognosis, monitoring

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13
Q

sarcoma

A

cytogenetic alteration
genetic analysis
diagnosis

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14
Q

thyroid

A

thyroglobulin
serology/ tissue IHC
screening, monitoring

calcitonin
serology
screening, prognosis, monitoring

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