Urology revision Flashcards
Testicular cancer stats and intro, RF
most common in young men- 25-45 year old
mainly-
Teratomas-v young, Seminomas-older young
Yolk sack
Lymphomas- OLD (>60)
RF
Undescended testes- 3-15x risk of cancer -mitigated with orchidopexy
HIV
White>black
Fhx
Scrotal lump Hx
fast growing-
how quickly is it growing
how detected
painful-usually infective
Painless- Cancer?
STI?
UTIsx
trauma
Lumps in abdo/neck
SOB- metastatic
smoke
examination self for a while
FHx
ddx for scrotal mass-esp for exams
Skin- sebaceous cyst, melanoma
Vaginal area-epidimytis (hard tender mass behind testes-settle on own), Torted
Hydrocele, Epidymial cyst,
testicular-cancer (hard craggy mass IN testes, rapid enlarge), orchitis, Lymphoma
Other-Lipoma of cord
Good intial Ix of scrotal masses
USS scrotum/testes–heterogenous lump IN testes
Bloods-BHCG, aFP, LDH are the markers
FBC, UE, CRP
Dipstick/culture for UTI
Testicular cancer markers
Not as useful for diagnsosis but crucial for monitor- esp before surgery
AFP-raised 70% in non seminoma
BHCG-raised across board, 10% of seminoma
LDH-more tumour bulk marker
Testicular cancer MX
Once diagnosed
biopsies are too slow
CTCAP isnt a bad idea but only if can be done fast for metastases
But you need orchidectomy -Inguinal approach (reduce seeding risk)
FAST-that’s the mx
CTCAP after-lung mets,
Chemotherapy-depends on CT and Path staging of cancer (generally - surveillance if no mets, Chemo upfront if mets)
testicular cancer survival
90%> if good (non metastatic)
>60% survival if metastatic
good cancer to have
Heamaturia Hx
How long
Previous?
LUTS
Fever/rigors?
Hx of stones, Flank pain
FHX of RCC etc
Dyes, smoker (TCC)
Is it infective or should I be worried
Exam- Look at the urine-real blood
Mass in Abdo
Ix of Heamaturia
Bedside dip, MSI
Bloods, UE
MSU
Gold standards—CT urogram and flexible cystoscopy
Non visible- do USS urogram first cause cancer less likely
TURBT (take a sample with scope) and biopsy with muscle for path
ddx of heamturia
Bladder cancer
renal cancer
stones
UTI
prostatic
visible heamturia- 20% cancer, most bladder
Invisible heamturia-5% cancer
LUTS, Weight loss etc-
Bladder cancer presentation
most common heamturia cancer (esp visible
Heamaturia reference guidelines
Urgent
over 45 with visible and no UTI
Over 60 and above with non visible + either WCC up, Dysuria
Bladder cancer staging and mx
TURBT (take a sample with scope) and biopsy with muscle for path
TNM stage-has it invaded muscle
bread muscle- radiotherapy, cystesctomy
Superficial- intravesical chemo
Or surveillance if low risk
Metastatic-chemo
Cystectomy follow up
get a stoma in Left illiac fossa- small urine catheter with spouted–usually a bit of bowel connecting the ureters to skin
Classifying hematuria for PACES
Anatomy approach
Renal (cancer n infection), Ureteric stones, Uretheric cancer, Bladder (cancer and infection), Prostate (cancer and infection), trauma, Urethra
or ddx
Infective, cancer, other
eg- pylonephritis, cystisis
bladder cancer (TCC), prostate, Renal (RCC)