Urology/Renal Flashcards
What is cryptorchidism?
the failure of testes to descend (one or both)
What are the characteristics of cryptorchidism?
- an undescended testicle is generally rare in full-time babies but common in baby boys born prematurely (30%)
- if not repaired risks infertility and malignancy
How is cryptorchidism dx?
-ultrasound may be helpful identifying undescended testicles in abdominal space
What is the tx of cryptorchidism?
treat with surgery (orchiopexy) by age 1
-the current recommendation is to correct as soon as possible after 4 months of age
What is cystitis?
bacterial UTIs are frequent cause of pediatric morbidity
- cystitis is when the infection is limited to the bladder
- girls have a 10-fold risk over boys
What is the most common bacterial pathogen in cases of UTI in children?
escherichia coli
What is the most significant risk factor for UTI in children?
the prescience of a urinary tract abnormality that causes stasis, obstruction of reflux
What are the symptoms of cystitis in older children?
similar to those in adults and include fever, frequency, urgency, dysuria, incontinence, abdominal pain, and hematuria
What are the symptoms in newborns and infants with UTI?
nonspecific signs, including fever hypothermia, jaundice, poor feeding, irritability, vomiting, failure to thrive, and sepsis
-strong, foul-smelling or cloudy urine may be noted
What is the dx of cystitis?
screening urinalysis indicates pyuria (>5 WBCs/HPF) in most children with UTI some children can have sterile pyuria with UTI
- urine culture is the gold standard for diagnosis, susceptibility testing should be performed
- in toilet-trained older children a midstream, a clean-catch method is usually satisfactory
- in infants and younger children, bladder catheterization or suprapubic collection is necessary in most cases to avoid contaminated samples
- bagged urine specimens are helpful only if negative
- asymptomatic bacteriuria is detected in 0.5-1% of children screened with urine culture
Who needs to get a renal and bladder ultrasonography (RBUS)?
- vesicoureteral reflux (VUR) is detected in 30-50% of children presenting with a UTI at <1 y/o
- the American academy of pediatrics (AAP) recommends RBUS for all infants and children 2 to 24 months following their first febrile UTI
- children of any age with recurrent febrile UTIs
- children of any age with a UTI who have a family history of renal or urologic disease, poor growth, or hypertension
- children who do not respond as expected to appropriate antimicrobial therapy
What is the tx of cystitis?
- cephalosporin x 14 days are the first-line oral agent in the treatment of UTI in children without genitourinary abnormalities
- first-generation cephalosporin (Keflex 50-100 mg/kg BID) for low risk of renal involvement
- second-generation (cefuroxime) or third-gen (cefixime, cefdinir, ceftibuten) for those with a high likelihood of renal involvement
- amoxicillin and ampicillin are not routinely recommended for empiric therapy because of the high rate of resistance of E. coli
What is enuresis?
involuntary loss of urine in child older than 5 years
-it may be nocturnal or daytime, or both and primary or secondary
When is successful bladder control usually achieved?
between the ages of 24 and 36 months, although many developmentally normal children take significantly longer
- clinically significant: occurs > two times per week for > three consecutive months or affects day to day life
- age: > 5 years old
- not caused by other substances
What is primary enuretics?
patients who have never successfully maintained a dry period
-primary nocturnal enuresis is thought to be due to delayed maturational control or inadequate levels of ADH secretions during sleep
What is secondary enuretics?
dry for several months before regular wetting occurs
How is enuresis dx?
enuresis should first be tested with a urinalysis and urine culture to rule out infection
-then a thorough history and physical with fluid intake, stool, and voiding diary should be compiled in order to investigate abnormal patterns seen in conditions like constipation or diabetes insidious
What is the tx of enuresis?
patients younger than 5 years of age do not require investigation or treatment, patients and family should be informed that bed-wetting is normal at their age and will likely resolve with time
What is the behavioral modification for the tx of enuresis?
nighttime audio alarm that sounds as soon as the child starts to urinate, eventually conditioning controlled bladder emptying before enuresis
What are the medications that can be used to tx enuresis?
desmopressin acetate (DDAVP) acts to concentrate the urine, if given in the evening, less urine is produced overnight, decreasing the likelihood of wetting
- with all therapies, the cure rate is 15% per year after the age of 5
- children who remain enuretic past age 8 have a 10% risk of never resolving their symptoms