Pulmonology Flashcards
What is acute bronchiolitis caused by?
RSV - commonly in fall and winter months
Who does acute bronchiolitis present in?
infants and young children
What are the symptoms of acute bronchiolitis?
tachypnea, respiratory distress, wheezing
How is acute bronchiolitis diagnosed?
nasal washing for RSV culture and antigen assay
-CXR = normal
What is the treatment of acute bronchiolitis?
- hospitalization if O2 situation <95-96%, age <3 months, RR > 70, nasal flaring, retractions, or atelectasis on CXR
- supportive = humidified O2, antipyretics, beta-agonist, nebulized racemic epinephrin, and steroids
- the only treatment demonstrated to improve bronchiolitis is oxygen
- ribavirin is given if sever lung or heart disease and in immunocompromised patients
What is given prophylaxis for acute bronchiolitis for special populations?
palivizumab - once per month for 5 months beginning in November (immunocompromised, premature infants, neuromuscular disorders)
What is asthma?
a chronic, reversible inflammatory airway disease with recurrent attacks of breathlessness and wheezing
How is asthma diagnosed and monitor?
with peak flow
- spirometry with pre and post-therapy (albuterol inhalation) readings
- decreased FEV1/FVC (75-80%)
- > 10% increase of FEV1 with bronchodilator therapy
What are the findings of spirometry for asthma?
- decreased FEV1 to FVC ratio <80% (you would expect the amount of air exhaled during the first second (FEV1) to be the greatest amount)
- in asthma, since there is an obstruction (inflammation) you will have a decreased FEV1 and therefore a reduced FEV1 to FVC ration
What is the treatment of mild intermittent asthma?
(<2x/week or <2 night/month) - SABA prn
What is the treatment of mild persistent asthma?
(>2x per week or 3-4 night/month) - low dose ICS daily
What is the treatment of moderate persistent asthma?
(daily sx or >1 night/week)
- low dose ICS + LABA daily
- medium dose ICS + LABA daily
What is the treatment of severe persistent asthma?
(sx severo times/day + nightly)
- high dose ICS + LABA daily
- hight dose ICS + LABA + oral steroids
What is the treatment for acute asthma?
oxygen, nebulized SABA< ipratropium bromide, and oral steroids
What is croup?
an infection of the upper airway, which obstructs breathing and causes a characteristic barking cough
What is croup caused by?
parainfluenza virus
Who is croup common in?
children 6 months - 3 years, fall and early winton months
What are the sings and symptoms of croup?
- baring cough and stridor
- steeple sign on PA CXR (narrowing trachea in the subglottic region)
What is the treatment of croup?
- supportive (air humidifier), antipyretics
- severe: IV fluids and nebulized racemic epinephrine, steroids
What is cystic fibrosis?
an autosomal recessive mutation in the CFTR gene
-abnormally thick mucus, difficultly clearing mucus
What is the presentation of cystic fibrosis?
recurrent repertory infections (especially pseudomonas), steatorrhea