Urology Pharm Flashcards

1
Q

BPH Treatment Meds

A

Alpha-1 blockers- 1st line
5 alpha-reductase inhibitors
Combo: Dutasteride-Tamulosin (Jalyn)
Tadalafil (Cialis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Alpha-1 blockers

A
Terazosin (Hytrin)
Doxazosin (Cardura)
Alfuzosin (Uroxatrol)*
Tamsulosin (Flomax)*
Silodosin (Rapaflo)*
used for BPH SYMPTOM MNGMT
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Alpha-1 blockers Side Effects

A

Most common are dizziness and orthostatic hypotension
Terazosin (Hytrin) and Doxazosin (Cardura) (cause more BP lowering than the others)
problems with ejactulation
DONT use with ED meds (phosphodiesterase-5 inhibitors)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

5 alpha-reductase inhibitors

A

Finasteride (Proscar)
Dutasteride (Avodart)
that provide long term decrease in prostate size and decreased need for prostatic surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

5 alpha-reductase inhibitors Side Effects

A

Decreased libido
Ejaculatory or erectile problems
Decreases serum PSA by 50%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Erectile Dysfunction Meds

A
Prostaglandin injectable:
Alprostadil
Phosphodiasterase inhibitors:
Tadalafil (Cialis)
Vardenafil (Levitra)
Sildenafil (Viagra)
Avanafil (Stendra)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Phosphodiasterase inhibitors Contraindications

A

Men taking nitrates

Caution with alpha-1 blockers due to risk for severe hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Testosterone replacement

A

To treat low testosterone levels in primary or secondary hypogonadism
Primary – Testes fail to produce testosterone
Secondary – Pituitary or hypothalamus malfunction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Urinary tract analgesics

A

Phenazopyridine (Pyridium)
Used for relief of SE of UTI: burning, itching, increased frequency, etc.
Do not use if GFR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Long Term therapy for Interstitial Cystitis

A

Pentosan (Elmiron)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Treatment of urgency, urgency-predominant mixed or OAB symptoms: Muscarinic antagonists/Antispasmodics

A
Oxybutynin (Ditropan) (Ditropan XL)
Tolterodine (Detrol) (Detrol LA)
Trospium (Sanctura), (Trospium XR)
Do not use in demented patients
Contraindications for antimuscarinic agents, Gastric retention, Angle closure glaucoma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly