GU Cancers Flashcards
Prostate cancer Risk Factors
Age: Rare in men younger than 40 y/o
Race: Higher rates in African-American men
Lower rate in Asian-American/Hispanic-Latino men
Family history: Two fold greater risk with first degree relative
Geography: High in North America
Stage T1
cancer is found in the prostate only. Cannot be felt by DRE or seen on imaging
Stage T2a and T2b
a tumor that is to small to be felt or seen on image test (2a) or a slightly larger tumor that can be felt on DRE (2b)
Stage T3
cancer has spread beyond the outer layers of the prostate into nearby tissues, and may have spread to seminal vesicles
Stage T4
any tumor that has spread to other parts of the body
American Cancer Society PSA screening
PSA testing with or without DRE for average risk at age 50
Screening not offered to men with life expectancy
Testicular cancer: Seminoma
Slow growing tumor
Found in men in their 30’s and 40’s
Very sensitive to radiation
Testicular cancer: Nonseminoma
More common and quicker growing 4 sub-types Embryonal carcinoma Yolk sac carcinoma Choriocarcinoma Teratoma Occur in teen years and early 40’s
Testicular cancer Staging
Stage I: Confined to the testicle
Stage II: Metastases to retroperitoneal nodes
Stage III: Metastases above the diaphragm or to visceral organs
Bladder Cancer Presentation
Most common is painless microscopic or gross hematuria (85%)
Frequency
Dysuria
Back or flank pain
Bladder Cancer Staging
Stage 0: papillary lesions relatively benign or carcinoma in situ
Stage 1: tumor invades submucosa or lamina propria
Stage 2: invasion into muscle
Stage 3: extends beyond muscle into the perivesical fat
Stage 4: extension into adjacent organs