Urology and Renal Flashcards
What pH is considered acidodic
< 7.35
what pH is considered alkalotic
> 7.45
if there is a elevated CO2 levels and decreased pH level what type of acid/based disorder is this?
respiratory acidosis
if there is a decreased CO2 levels and increased pH level what type of acid/based disorder is this?
respiratory alkalosis
if there is a decreased HCO3 and pH level, what type of acid/based disorder is this?
metabolic alkalosis
if a patient has an elevated HCO3 and pH level, what type of acid/based disorder is this?
metabolic alkalosis
a 78-year-old woman, G5P5, who presents to establish care. She is healthy and denies any additional problems. However, when specifically asked, she admits to having urinary incontinence for several years and reports that symptoms have recently worsened. The patient experiences the need to void almost hourly and she now uses four to five adult incontinence pads per day to manage the urine she leaks. She has had occasional accidents while asleep at night as well. She denies leaking urine with coughing or sneezing.
what is the likely diagnosis?
urge incontinence
what are the diagnostic tests for urge incontinence
urodynamic testing
what is the treatment of urge incontinence
Bladder-training exercises
can due anticholinergics (oxybutynin) and TCAs (imipramine)
what is stress incontience
weakness of pelvic floor - urine leakage due to abrupt increases in intra-abdominal pressure (ex. with coughing, sneezing, laughing, bending or lifting)
a 68-year-old woman who presents to your office with leakage of urine when she sneezes, laughs, or coughs. She reports that these symptoms strictly occur during the day and never at night. She denies any subjective fever, dysuria, or hematuria. Pelvic examination is notable for a protrusion from the anterior vagina.
what is the likely diagnosis?
Stress incontinence
what is the treatment of stress incontinence
kegel exercises to strengthen pelvic floor musculature
vaginal estrogens
pessary
surgery is an option for mid-urethral sling
what is overflow incontience
impaired detrusor contractility - occurs when urinary retention leads to bladder distrention and overflow of urine through urethra
a 67-year-old man comes to the clinic because of urinary incontinence with the frequent loss of small amounts of urine for the past 2 weeks. He describes having difficulty initiating urination or telling when or if his bladder is full or empty. He denies frequency, urgency, or bowel dysfunction. Past medical history is significant for stroke 1 year ago in addition to hypertension and coronary artery disease. Past surgical history is significant for lower back surgery one month ago after a car accident. Physical examination shows decreased sphincter tone and 110 ml of post-void residual urine. Diagnostic tests show normal bladder capacity, no sign of infection, normal prostate-specific antigen levels, and normal creatinine.
what is the likely diagnosis?
overflow incontinence
how is overflow incontience diagnosed?
urodynamic testing
elevated postvoid residual volume
what is the best management of overflow incontinence
intermittent self-catheterization
what are other medical management options for stress incontinence
cholinergic agents (bethanechol) to increase bladder contractions
alpha blockers (terazosin, doxazosin) to decrease sphincter resistance
a 38-year-old military veteran who served three tours in Afghanistan presents to your clinic complaining of urinary incontinence. He was injured during his last tour of duty when he stepped on an improvised explosive device and lost the bottom of both of his legs. He ambulates much of the time in a wheelchair. He lives alone with little assistance. He reports a history of hypertension and was recently prescribed lisinopril + hydrochlorothiazide. He denies tobacco and alcohol use but drinks about 4-5 cups of coffee per day. He has a normal exam with a normal urinalysis and normal prostate-specific antigen.
What is the likely diagnosis?
functional incontinence
what is the treatment for functional incontinence
scheduled voiding times and removal of precipitating factors
what is the number one cause of renal vascular disease
diabetic kidney disease
other causes: HTN, Smoking, Vascular disease aka rental artery stenosis, glomerular disease, renal cyst, genetics
what is Azotemia
elevated BUN concentration
what are causes of prerenal injury
due to decreased blood flow to the kidneys
- Hypovolemia
- NSAIDs, IV contrast, ACEi and ARBs
-
what is the treatment of prerenal injury
IV fluids will help improve creatine
what are causes of intrinsic kidney injury
Nephrotoxic drugs = aminoglycosides (gentamicin)
cyclosporine
Tumor lysis syndrome
Vasculitis (SLE, sarcoidosis)
crystsals from gout
Myoglobin from rhabdomyolysis
what is the hallmark sign of intrinsic kidney injury
WBC casts
what is the treatment of intrinsic kidney injury
IV fluids remove drugs if present and somteimes lasix to get the kidneys moving
what are causes of postrenal kidney injury
kidney stones
BPH, tumors
congential/structural abnormalities