Urology Flashcards

0
Q

Furosemide

A

A. Loop diuretics
B. act on thick ascending limb of loop of henle where it inhibit reabsorption of Na/2Cl/K
C. Hypertension

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1
Q

Hydrocholorothiazide

A

A. Thiazide diuretics
B. acts on DCT - inhibit reabsorption of Na / Cl
C. Hypertension

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2
Q

Torasemide

A

A. Loop diuretics
B. act on thick ascending limb of loop of henle where it inhibit reabsorption of Na/2Cl/K
C. Hypertension

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3
Q

Eplerenone

A

A. Aldosterone antagonist (mineralcorticoid R blocker)
B. inhibit physiologic effect if aldosterone - increase excretion of Na and decrease excretion of K
C. Hypertension

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4
Q

Mannitol

A

A. Osmotic diuretics
B. act on PCT and thick descending limb of loop of henle where it inhibits reabsorption of Na and H2O
C. Hypertension, elevated intraocular pressure, prevent oliguric phase of acute renal failure

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5
Q

Tamsulosin

A

A. Alpha 1-R blocker
B. blocks alpha R on bladder and prostate - SM relaxation
C. Benign prostatic hyperplasia, help passage of kidney stones

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6
Q

Doxazosine

A

A. Alpha1- R blocker
B. binds to alpha R on prostate and bladder- SM relaxation
Binds to alpha1 R - vasodilation - decrease PVR - drop of BP
C. Hypertension, BPH, urinary outflow obstruction

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7
Q

Finasteride

A

A. 5 alpha reductase inhibitor (steroid)
B. blocks conversion of testosterone to dihydritesttoaterine (DHT)
C. BPH, male pattern baldness

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8
Q

Dutaseride

A

A. 5 alpha reductase inhibitor (steroid)
B. blocks conversion of testosterone to dihydritesttoaterine (DHT)
C. BPH

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9
Q

Oxybutynin

A

A. Muscarinic cholinoblocker (selective)
B. inhibit Ach binding to M-R - SM relaxation of the bladder
C. Over active bladder

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10
Q

Tolterodine

A

A. Muscarinic cholinoblocker (non- selective)
B. inhibit Ach binding to M-R - SM relaxation of the bladder
C. Over active bladder

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11
Q

Solifenacin

A

A. Muscarinic cholinoblocker (selective)
B. inhibit Ach binding to M-R - SM relaxation of the bladder
C. Over active bladder

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12
Q

Desmopressin

A

A. Anti diuretic H (synthetic replacement of vasopressin)
B. increases water reabsorption - decrease urine production
Increase plasma factor VIII, plasminogen activator - improves blood clotting
C. Diabetes, polyuria, haemophilia A, von Willebrand diseases

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13
Q

Sildenafil/ Viagra

A

A. Selective phosphodiesterase 5 inhibitor
B. selective inhibitor of PDE in penis and clitoris - vasodilation
Also used in patients with pulmonary HT- vasodilation
C. ED, pulmonary HT

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14
Q

Tadalafil/ Cialis

A

A. Selective phosphodiesterase 5 inhibitor (slower acting than Viagra)
B. selective inhibitor of PDE in penis and clitoris - vasodilation
C. ED

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15
Q

Methylergometrine

A

A. Uterus plasmodia agent
B. cause contraction of uterine SM. Also produce vasoconstriction
C. Prevention of postpartum haemorrhage

16
Q

Atosiban

A

A. Oxytocin R antagonist
B. inhibit action if oxytocin + vasopressin - suppress labour by inhibiting uterine contraction
C. Labour depressant