Respiratory System

Question 0

Dextromethorphan

Answer 0

A. Antitussive
B. acts centrally by inhibiting the cough center in the brain - elevating the cough threshold
C. Common colds, temporary relief of cough, sneezing

Question 1

Nikethamide

Answer 1

A. Respiratory stimulant
B. centrally acting to stimulate the respiratory center
C. Against overdose of drugs, for mountain climbers

Question 2

Prenoxdiazine

Answer 2

A.antitussive
B.acts peripherally- acts in respiratory system by anazthesing the local nerve endings
C.non productive cough

Question 3

Guaifenesin

Answer 3

A.expectorant
B.work by increasing the amount of fluid in respiratory tract which in turn increase flow and clearance
C.temporarily relief of productive cough, nasal secretions

Question 4

Acetylcysteine

Answer 4

A.mucolytic agent
B.breaks disulfid binds -decrease if viscosity - airway clearance. Facilitate their removal by coughing
C. Treatment of abnormal mucous production in different diseases (CF), overdose

Question 5

Ambroxol

Answer 5

A.mucolytic agent
B.release surfactant - acts as anti glue factor by decreasing adhesion of mucous to bronchial wall
C. Treatment of respiratory diseases associated with excessive mucous (CF)

Question 6

Fenoterol

Answer 6

A. Beta 2 agonist
B. cause bronchodilation
C. Open up airways in lungs, asthma

Question 7

Salmeterol

Answer 7

A. Long acting beta 2 agonist (selective)
B. bronchodilation
C. Asthma (long term asthma controller)

Question 8

Ipratropium

Answer 8

A. Antimuscarinic R blocker (short acting)
B. blocks M-R in smooth muscle of the bronchi and cause dilation
C. COPD, acute asthma

Question 9

Ipratropium/ Feneterol

Answer 9

A. Combination therapy (anti Muscatinic and Beta 2 agonist)
B. cause bronchodilation
C. COPD, asthma

Question 10

Theophylline

Answer 10

A. Xanthine derivate
B. blocks phosphodiesterase - increase cAMP - smooth muscle relaxation - vasodilation
C.COPD, chronic bronchitis and emphysema

Question 11

Aminophylline

Answer 11

A.xanthine derivate
B. blocks phosphodiesterase - increase cAMP - smooth muscle relaxation
C. Asthma, COPD

Question 12

Beclometasone

Answer 12

A. Corticosteroid
B. inhibits inflammatory cells and prevents release of inflammatory mediators
C. Long term prevention of broncho spasms in patients with asthma

Question 13

Methylprednisolon

Answer 13

A. Glucocorticoid
B. anti inflammatory and immunosuppressant agent
C. Asthma, COPD

Question 14

Sodium cromoglicate

Answer 14

A. Mast cell stabiliser
B. prevents the release of histamine and other mediators from mast cells
C. Bronchial asthma, broncho spasm, asthma

Question 15

Montelukast

Answer 15

A. Leukotriene R anatagonist
B. binds to R in smooth muscle in airways and inhibit leukotriene R - bronchodilation
C. Asthma in adults and children, prevents exercise induced broncho constriction, allergic rhinitis

Question 16

Xylometazoline

Answer 16

A. Vasoconstrictor alpha 1&2 agonist
B. causes vasoconstriction in BV in the nose - decrease the fluid release from the nose
C. Nasal decongestant

Question 17

Azelastine

Answer 17

A. Topical H1- R antagonist
B. inhibits release if histamine and other mediators involved in allergic reactions
C. Seasonal allergic rhinitis

Question 18

Budesonide

Answer 18

A. Corticosteroid (weak mineralcorticoid activity)
B. anti inflammatory agent which causes bronchodilation
C. Long term prevention of broncho spasm, Crohn’s disease