GIT System Flashcards
Aluminii hydroxidum/ magnesii hydroxidum
A. Anti acids
B. are buffers that acts locally in the stomach by reacting with H to increase pH = neutralisation
C. Dyspepsia (indigestion)
Tinctura absinthii
A. Appetite stimulator
B. increase the appetite
C. Loss of appetite
Omeprazolum
A. Proton pump inhibitor
B. inhibits proton pump located on the parietal cells in stomach - decrease secretion of HCl
C. Dyspepsia with GER, peptic ulcer
Ranitidine
A. H2 R antagonist
B. inhibits binding of histamine to
H2 R- decrease of cAMP - decrease secretion H (gastric acid)
C. GERD, dyspepsia
Sucralfatum
A. Mucous membrane protective agent (weak anti acid)
B. binds to mucous membrane and acts as a barrier to acid, pepsin, bike
C. Peptic ulcers
Dimenhydrinate
A. Antihistamine H1-R blocker (antiemetic drug)
B. blocks H1- R and probably also muscarinic R in the nerves connecting vestibular organ with the vomiting center in the brain
C. Motion induced nausea, vomiting in pregnancy
Aprepitantum
A. Neurokinin 1 antagonist (antiemetic drug)
B. blocks signals of NK-R - prevents vomiting
C. Chemotherapy induced nausea and vomiting, postoperative vomiting and nausea
Ondansetrone
A. Serotonin 5HT3 - R antagonist
B. blocks 5HT3 R in both brainstem and nerve endings leading to a decreased release of serotonin (serotonin activates vomiting reflex)
C. Chemotherapy induced nausea and vomiting
Metoclopramidum
A.antiemetic agent (dopamine 2R antagonist)
B. Inhibit gastric SM relaxation produced by dopamine
C. GERD, nausea and vomiting
Sodium ursodexycholic
A. Choletropic agent (secondary bile acids)
B. regulates cholesterol by - decreasing uptake of cholesterol from intestines
C. Used to treat cholesterol stones non surgically
Drotaverinum
A. Antispasmotic drug
B. selective inhibitor of phosphodiesterase 4. Has analgesic effect (painkiller)
C. Used in treatment of renal cholic
Pain caused by smooth muscle spasm
Bisacodylum
A. Intestine irritating laxantia
B. stimulate nerve endings in the gut - leading to increased peristaltics
C.constipation
Extr. Folium Sennae
A. Intestine irritating laxantia
B. stimulate nerve endings in the gut - leading to increased peristaltics
C. Constipation
Macrogolum
A. Osmotically acting laxantia
B. synthetical disaccharide - working by attracting water in the intestine
C. Constipation, bowel cleaning before surgery and medical examination
Lactulsosum
A. Osmotically acting laxantia
B. synthetical disaccharide - working by attracting water in the intestine
C. Constipation, bowel cleaning before surgery and medical examination