Urology 2 Flashcards
Presentation of obstructive uropathy?
upper:
loin to groin pain
oliguria
vomiting
impaired renal function
lower:
urine retention
difficulty passing urine
impaired renal function
Causes of obstructive uropathy?
upper:
stones
tumour
strictures
retroperitoneal fibrosis
bladder cancer
ureterocoele
lower:
BPH
prostate cancer
bladder cancer
urethral strictures
neurogenic bladder
Causes of neurogenic bladder?
MS
DM
stroke
Parkinson’s
spinal cord injury
spina bifida
Mx of obstructive uropathy?
bypassing the obstruction
nephrostomy in upper
urethral or suprapubic catheter in lower
Complications of obstructive uropathy?
pain
AKI
CKD
infection
hydronephrosis
urinary retention
overflow incontinence
Indications for urinary catheter?
urinary retention
neurogenic bladder
surgery
output monitoring
bladder irrigation
delivery of meds
Prostate exam results?
BPH -> smooth, symmetrical and slightly soft, with maintained central sulcus
prostate cancer -> firm/hard, asymmetrical, irregular, craggy and loss of central sulcus
Mx of BPH?
medical:
alpha blockers (tamsulosin- immediate relief of symptoms)
5-alpha-reductase inhibitors (finasteride- decrease size of prostate over 6 months)
surgical:
TURP
Complications of TURP?
urinary incontinence
erectile dysfunction
retrograde ejaculation
urethral strictures
failure to resolve symptoms
TURP syndrome
RFs for prostate cancer?
age
FHx
Black
tall stature
anabolic steroids
Presentation of prostate cancer?
asymptomatic
LUTS
haematuria
erectile dysfunction
mets
Causes of raised PSA?
prostate cancer
BPH
prostatitis
UTI
vigorous exercise (cycling)
recent ejaculation
prostate biopsy
DRE
Investigations for prostate cancer?
multiparametric MRI
TRUS biopsy
trans-perineal biopsy
isotope bone scan
Gleason scoring of prostate cancer?
grading based on histology
out of 10
the grade of the most prevalent pattern in the biopsy + the grade of the second most prevalent pattern in the biopsy
6 low risk
7 intermediate
8-10 high risk
Grading of prostate cancer?
Gleason score
TNM
Mx of prostate cancer?
watch and wait
TURP
external beam radiotherapy/brachytherapy
radical prostatectomy
hormone therapy (GnRH agonists, androgen receptor antagonists)
Most common organisms causing epididymo-orchitis?
E coli
Neisseria gonorrhoea
Chlamydia
mumps
Diagnosing epididymo-orchitis?
differentiate if caused by STI or enteric organism
urine C&S
NAAT
charcoal swab
saliva swab
serum antibodies for mumps
US
Mx for epididymo-orchitis?
Enteric:
ofloxacin
levofloxacin
co-amoxiclav
STI:
IM ceftriaxone (gonorrhoea)
doxycycline (chlamydia)