Urological Malignancy - Wilms' Tumour

Question 1

What is Wilms’ Tumour?

Answer 1

A nephroblastoma - childhood tumour of primitive renal tubules and mesenchymal cells.

Question 2

Epidemiology of Wilms’ Tumour

Answer 2

Presents in kids under 5 (median : 3).

Question 3

Clinical Features of Wilms’ Tumours (3).

Answer 3

1. Abdominal Mass (commonest).
2. Painless Haematuria.
3. Abdominal Pain.

Question 4

Indication for Review.

Answer 4

Children with an unexplained enlarged abdominal mass needs a paediatric review within 48 hours.

Question 5

Investigation of Wilms’ Tumour (3).

Answer 5

1. Initial : US Abdomen.
2. Staging : CT/MRI.
3. Diagnosis : Biopsy.

Question 6

Management of Wilms’ Tumour (2).

Answer 6

1. Surgical Excision - Nephrectomy.

2. Adjuvant Chemotherapy/Radiotherapy.