Urologic Flashcards
Neurological causes for urinary incontinence:
____
Spinal injury
Normal-pressure hydrocephalus
Multiple sclerosis
Potentially reversible causes for urinary incontinence:
diuretics
UTIs
____
Stool impaction
__ incontinence 2/2
urethral hyper-mobility
increased intra abd pressure
Stress
__ incontinence 2/2
autonomous contractions of the detrusor muscle
Urge
Treatment for urge incontinence
Anticholinergic (M3) medication (oxybutynin*)
Sympathomimetics (mirabegron**)
—————————————————-
*M3 antagonist causes antispasmodic effect on bladder smooth muscle
**Beta 3 agonist relaxes detrusor smooth muscle which increases the bladder’s storage capacity
\_\_ incontinence 2/2 Loss of or weak detrusor contractility due to: Neurogenic bladder (multiple sclerosis) Neuropathy (diabetes mellitus) Spinal cord injuries BPH
Overflow
Overflow incontinence 2/2
Absence of an urge to urinate/Incomplete bladder emptying → bladder overfilling → chronically distended bladder with ↑ bladder pressure → dribbling of urine (leak) when ___ pressure > sphincter outlet pressure
intravesical
Post void residual volume >50 ml in
Overflow incontinence treatment
Acute settings: ____
Long term: ___
intermittent catheterization
Scheduled voiding daily
Type of incontinence seen in multiple sclerosis or spinal cord injury
____ → simultaneous contractions of the detrusor muscle + urethral sphincter contraction → urine leaks
Detrusor sphincter dyssynergia
urinary retention and leaking without an associated urge to void
Work up for incontinence:
1st test → ____
If negative get:
→ ____
→ ____
- UA & urine culture (r/o UTI)
- Post void residual volume
- Renal ultrasound
1st line treatment for stress incontinence
Weight loss
decrease consumption of alcohol, caffeine
Kegel’s
1st line treatment for urge incontinence
Bladder training:
- scheduled voiding
- holding for as long as possible
- relaxation/distraction techniques
*If that fails or sxs affect ADLs give oxybutynin or mirabegron
Stress incontinence treatment if refractory to 1st line or affecting quality of life
mid urethral urinary sling
The most common (∼ 95%) type of cancer of the bladder, ureter, renal pelvis, and proximal urethra in males
Transitional cell (urothelial) carcinoma
*Present from proximal urethra to renal pelvis
Urinary tract cancer risk factors:
___ use
Prolonged (occupational) exposure to ____
_____ ( Africa and the Middle East)
cyclophosphamide
Tobacco
Carcinogens (dyes, heavy metals, plastics, aromatic amines like benzidine)
Schistosomiasis
Painless gross hematuria throughout micturition (most commonly)
&
Irritative voiding symptoms (dysuria, urinary frequency, urgency)
associated with ___ carcinoma
Bladder
Diagnostics for suspected Urinary tract cancer:
- ___ indicated in all patients with hematuria
- _____ Imaging modality of choice to examine the entire urinary tract.
- ___ & biopsy direct visualization of urethral and bladder mucosa
Urinalysis
CT urography
Cystoscopy
Treatment for bladder cancer:
____
+/-
chemotherapy or chemoradiation
Radical cystectomy
Painless gross hematuria at the beginning of micturition
Bladder outlet obstruction
Irritative voiding symptoms
associated with ___ carcinoma
Urethral
Painless gross hematuria throughout micturition
Flank pain
associated with Carcinoma of ____ & ____
Renal pelvis (Kidney)
&
Ureters
Upper urinary tract obstruction causes: \_\_\_ Renal pelvis carcinoma Ureteropelvic junction obstruction \_\_\_\_ Ureteral carcinoma
Nephrolithiasis
Ureteral stricture
(Stones, Strictures, Tumors
cause Upper urinary tract obstructions)
Lower urinary tract obstruction (bladder outlet obstruction) causes:
Bladder carcinoma Neurogenic bladder BPH/ prostate cancer \_\_\_\_\_ (Congenital) urethral stricture \_\_\_\_ (Mechanical)
posterior urethral valves
kinked/plugged catheter
Urinary retention
Suprapubic pain and mild distention
Palpable bladder
symptoms of what?
Lower urinary tract obstruction
bladder outlet obstruction
Labs in urinary tract obstruction
(↑/↓) BUN & Cr
(hyper/hypo)-kalemia
↑ BUN & Cr
hyperkalemia