Urolithiasis Flashcards
At what locations are kidneys stones most likely to obstruct?
Pelvic-ureter jucntion
Crossing the ilium at the pelvic brim
Vesico-ureteric junction
What are the risk factors for urolithiasis?
Male Age 20-50 years Comorbidities <1200ml fluid intake / day High animal protein/salt, low calcium diet Sedentary lifestyle Hot climate
What is the most common type of kidney stone?
Calcium oxalate
What is the likely cause of cysteine stones?
Genetic
What condition is associated with uric acid stones?
Gout
What are struvite stones composed of?
Magnesium
Ammonium
Phosphate
What type of kidney stones are associated with infection?
Struvite stones
What type of stones are stag horn calculi usually?
Struvite stones
What is the cause of xanthine stones?
Genetic enzyme deficiency resulting in a build up on xanthine deposits
What is the saturation product?
The level at which no more solute will dissolve in solution without a change in pH or temperature
What is the formation product?
The level at which spontaneous stone formation occurs
What factors increase the likelihood of kidney stone formation?
Low volume, low pH, low citrate, low magnesium, high uric acid, high calcium, high oxalate
How can kidney stones present?
Incidental finding
Colicky loin to groin pain, patient cannot settle and can lie still
Visible/non-visible haematuria
Sepsis
What initial investigations into urolithiasis should eb conducted?
U&Es, CRP, FBC, urinalysis, CT
What biochemical tests should be conducted for a first kidney stone?
Calcium Urate Urine dip MSS Sodium nitroprusside Stone analysis