Urinary Tract

Question 0

Tolterodine/ detrol

Answer 0

Anticholinergic
Urge incontinence
Competitive antagonism of M2 & M3 muscarinic ACH receptors
Fewer interactions with drugs metabolized by cyp450

Question 1

Oxybutynin/ ditropan

Answer 1

Anticholinergic
Frequent urination, urge incontinence, hyperhydrosis
Competitive antagonism of M3 muscarinic ACH receptors
Dry mouth, eyes, constipation, blurred vision, diminished sweating

Question 2

Imipramine/ tofranil

Answer 2

Tricyclics antidepressant
Urge incontenence, enuresis in children
Blocks reputable of serotonin & NE- diminishes uptake of ACH in SM
Overdose may cause heart block  
Given at bedtime

Question 3

Tamsulosin/ flomax

Answer 3

α-1 receptor antagonist
BPH
SM relaxation, selective for α-1A receptors in prostate(vs. α-1B in blood vessels)

Question 4

Finasteride/ proscar

Answer 4

5-α reductase inhibitor
BPH. Lower doses marketed as propecia for hair loss
Blocks conversion of testosterone to dihydrotestosterone
Impotency
CATEGORY X

Question 5

Phenazopryidine/ pyridium

Answer 5

Pain, burning, and urge of cystitis
Unknown MOA 
Color change of urine & tears- may stain contact lenses
HA, dizziness
100-200mg tabs 2-3x/day