Urinary System Dr. Yan Flashcards

1
Q

Where does the urinary system originate from?

A

intermediate mesoderm

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2
Q

What are the three successive kidneys?

A

pronephros
mesonephros
metanephros

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3
Q

Where does the pronephros come from and is it functional?

A

cervical region, non functional

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4
Q

How long does the pronephros exist for?

A

only during week 4

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5
Q

When does the mesonephros appear and disappear?

A

appears at week 4 and disappears at end of 2 months (except for mesonephric duct in males)

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6
Q

Where does the mesonephros com form?

A

thoracolumbar

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7
Q

When does the metanephros appear?

A

week 5

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8
Q

which kidney is the definitive kidney?

A

metanephros

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9
Q

Which kidney is the inducer?

A

mesonephros

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10
Q

Where does the mesonephros kidney originate from?

A

intermediate mesoderm

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11
Q

Describe the process occurring at week 4 starting with the excretory tubule?

A

excretory tubule-> glomerulus and bowman’s corpuscle= renal corpuscle-> mesonephric (Wolffian) duct

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12
Q

What does the renal corpuscle turn into during week 4?

A

mesonephric duct

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13
Q

What does the urogential ridge begin to turn into at the 2nd month?

A

gonads

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14
Q

By the end of the 2nd month, (blank) in the males go to ejaculatory duct and females disappear

A

mesonephric ducts

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15
Q

Is the second kidney functional?

A

yes

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16
Q

When does the metanephros (definitive kidney) appear?

A

week 5

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17
Q

Ureteric bud outgrown from the mesonephric duct penetrate metanephric tissue and induces (blank)

A

metanephric blastema (from intermediate mesoderm).

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18
Q

the ureteric bud continues to divide to form what?

A

ureter, renal pelvis, major and minor calyces, and collecting tubules

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19
Q

when do you get the creation of the ureter and renal pelvis?

A

6th week

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20
Q

When do you get the creation of the minor and major calyxes?

A

7th week

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21
Q

When do you get the creation of the collecting tubules?

A

newborn

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22
Q

What make the renal pyramids?

A

collecting tubules

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23
Q

What is formed by the metanephric mesoderm induced by ureteric bud?

A

filtration system

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24
Q

What is the filtration system formed by?

A

metanephric mesoderm induced by uretic bud

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25
Q

Describe the formation of the filtration system?

A

metanephric tissue cap-> renal vesicles-> s-shaped tubule-> capillaries grow into-> glomeruli

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26
Q

What is the excretory unit?

A

nephron

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27
Q

What creates the metanephric tissue caps?

A

the endothelium secretes signals to induce formation of the mesenchymal cells to turn into metanephric tissue caps

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28
Q

kidney development is dependent upon (blank).

A

epithelial mesenchymal interactions

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29
Q

(blank), expressed in mesenenchyme, stimulate branching and growth of the ureteric bud.

A

growth factors

30
Q

What is this?

cyst formation from collecting tubules; renal failure in infancy or childhood

A

Autosomal recessive polycystic kidney disease

31
Q

What is this?

cyst formation from all segments of the nephron, no renal failure until adulthood

A

Autosomal dominant polycystic kidney disease

32
Q

What is caused by early splitting of the ureteric bud?

A

duplication of ureter

33
Q

Does partial splitting or complete splitting of the ureter ever occur?

A

yes

34
Q

The earlier the splitting occurs, the more likely you will get (blank) split which is much more severe

A

complete

35
Q

What is an ectopic ureter opening?

A

ureter connected to inappropriate area

36
Q

With growht, (blank) ascends and (blank) descends

A

kidney, gonads

37
Q

Initially you have only one entry into the cloacal what is it?

A

mesonephric duct

38
Q

As the metanephric duct forms and grows what happens to the mesonephric system?

A

majority of it degenerates with some remnants in contact with the gonad remaining

39
Q

the (blank) of the urogenital sinus will form the prostate

A

mesenchyme

40
Q

What is the ascent of the kidney caused by?

A

decreased body curvature and by growth of the body in the lumbar and sacral regions

41
Q

Where do kidney form in?

A

pelvis

42
Q

If kidney fuse and get stuck on inferior mesenteric artery, what arises?

A

a horshoe kidney

43
Q

If you have a horseshoe kidney what will it get stuck on?

A

inferior mesenteric artery.

44
Q

(blank) divides into urogenital sinus (anterior) and the anal canal (posterior) by urorectal septum.

A

Cloaca

45
Q

Cloaca divides into urogenital sinus (anterior) and the anal canal (posterior) by (blank) septum.

A

urorectal

46
Q

What is the structural opening of the urinary, intestinal and reproductive systems

A

cloaca

47
Q

What are the three division of the urogenital sinus?

A

upper, pelvic, and lower phallic part

48
Q

What part of the urogenial sinus is the largest, and the bladder is here?

A

upper

49
Q

What part of the urogenital sinus has the prostatic and membranous parts of the urethra?

A

pelvic part

50
Q

What part of the urogenital sinus differs between two sexes?

A

lower phallic part (penile urethra, female urethra)

51
Q

What does the urogenital sinus turn into?

A

urinary bladder and definitive sinus

52
Q

Where are the mesonephric ducts absorbed?

A

into the bladder wall

53
Q

Mesonephric ducts are absorbed into the bladder wall, off of the mesonephric ducts the (blank) forms. Then the ureter then moves and enters the (blank) separately.

A

ureter

bladder

54
Q

Which direction does the newly formed ureter travel?

A

cranially

55
Q

(blank) move lower to enter urethra where prostate forms and ducts become ejaculatory ducts in males.

A

mesonpehric ducts

56
Q

parts of ducts incorporated in bladder forms (blank) area of the bladder

A

trigone

57
Q

Both mesonephric ducts and ureters originate from the (blank)

A

mesoderm

58
Q

The mucosa of the bladder formed by the incorporatio of the ducts is also (blank)

A

mesodermal

59
Q

With times, the mesodermal lining of the trigone is replaced by (blank)

A

endodermal epithelium

60
Q

What are three major bladder defects?

A

urachal fistula
exstrophy of the bladder
epispadias

61
Q

What is a the remnant of a short term connection from the bladder to the umbilicus?

A

Urcharus or old allantois

62
Q

What is the old allantois/urachus of the bladder to umbilicus specifically named?

A

the median umbilical ligament

63
Q

What happens if the allantois of the uracha persists?

A

a urachal fistula forms

64
Q

What is it called if only a local area of of allantois persists resulting in cystic dilation?

A

urachal cyst

65
Q

What is it called if the upper part of the allantois persists?

A

urachal sinus

66
Q

What is a sign of urachal fistula??

A

urine drains from umbilicus

67
Q

(blank) is a malformation in which the urethra opens on the dorsum of the penis; frequently associated with exstrophy of the bladder.

A

Epispadias

68
Q

What is a constant feature of exstrophy of the bladder?

A

epispadias

69
Q

What is exstrophy of the bladder?

A

it is a ventral body wall defect where the bladder mucosa is exposed

70
Q

A lack of mesodermal migration into the region between the umbilicus and genital tubercle, followed by rupture of the thin layer of ectoderm results in what?

A

exstrophy of the bladder