Urinary/Renal Flashcards

1
Q

five functions of the kidney

A

Blood filtration, reabsorption, secretion
Fluid balance regulation
Blood pressure via fluid balances
Acid/base balance regulation through electrolytes
Hormone production (erythropoietin)

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2
Q

two hormones responsible for fluid balance regulation

A

ADH (anti diuretic hormone)
Aldosterone

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3
Q

The rate at which plasma is filtered as it goes through the glomerulus

A

glomerular filtration rate

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4
Q

Normally, about _____ of the plasma is removed from circulation every minute

A

25%

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5
Q

ADH (anti diuretic hormone) is released by the ______ ______ and acts on the _____ ______ _____, causing _____ water reabsorbtion

A

pituitary gland
distal convoluted tubule
more

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6
Q

helps regulate your blood pressure by managing the levels of sodium (salt) and potassium in your blood and impacting blood volume

A

aldosterone

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7
Q

Many drugs must be used with caution or at ______ ______ for patients with renal insufficiency.

A

modified doses

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8
Q

three uses of osmotic diuretics

A

decrease IOP
reduce cerebral edema
ascites

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9
Q

______ diuretics have a longer duration than loop diuretics

A

thiazide

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10
Q

two uses for thiazide diuretics

A

nephrogenic diabetes insipidus
hypertension in dogs

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11
Q

potassium sparing diuretics work by antagonizing _______

A

aldosterone

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12
Q

what diuretic should be avoided in addison’s patients

A

potassium sparing diurects

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13
Q

two indications for carbonic anhydrase inhibitor diuretics

A

Reduce IOP (Glaucoma-open angle)
Metabolic alkalosis

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14
Q

what do cholinergic agonist/parasympathomimetic drugs mimic

A

acetylcholine

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15
Q

two urinary indications for cholinergic agonist/parasympathomimetic drugs

A

Used to improve bladder tone
Correct bladder atony which is common following obstruction

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16
Q

lack of normal tone or tension

A

atony

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17
Q

adverse effect of anticholinergic/parasympatholytic drugs

A

decreased gastric motility

18
Q

two uses of adrenergic antagonists/alpha adrenergic antagonist (alpha blockers) for urinary issues

A

Reduce urethra sphincter tone—relax and PEEE!!!!
Mild hypertension (Vasodilation) associated with chronic renal failure

19
Q

what do adrenergic antagonists/beta adrenergic antagonist (beta blockers) block

A

catecholamines

20
Q

what do ACE inhibitors reduce

A

vasoconstriction

21
Q

two uses for ACE inhibitors

A

Used to treat hypertension (Chronic renal failure)
Protein losing glomerulonephritis

22
Q

inflammation and damage to the filtering part of the kidneys (glomerulus)

A

glomerulonephritis

23
Q

what are calcium channel blockers/vasodilators used for

A

hypertension due to chronic renal failure

24
Q

what is ADH (Vasopressin) used to treat

A

Treats diabetes insipidus PU/PD without hyperglycemia

25
used to dissolve crystals and stones resulting from alkaline urine.
urinary acidifiers
26
why are urinary acidifiers no longer used
because we have pH modifying urinary diets
27
urinary acidifiers are not used for what
kidney/liver disease
28
used to prevent Ammonium acid urate, calcium oxalate, and cystine uroliths
urinary alkalizers
29
used to prevent uric acid (gout)
Xanthine Oxidase inhibitors
30
three causes for urinary incontinence
neurogenic (nervous system) non neurogenic (physical, hormonal, etc) behavioral
31
which urinary incontinence drug is risky and estrogen based
Diethylstilbestrol
32
which urinary incontinence drug is safe
Phenylpropanolamine
33
Phenylpropanolamine works on _____ muscle
smooth
34
urinary tract analgesic drug
Phenazopyradine
35
do not use Phenazopyradine in what species
cats
36
what are tricyclic antidepressants (amitriptyline) used for
FLUTD cats
37
what does FLUTD mean
Feline lower urinary tract disease
38
Lubricate lining of bladder and urethra – crystals and bacteria do not adhere
Glycosaminoglycans (GAGs)
39
reinforce GAGs effect
Pentosan Polysulfated Sodium
40
Phosphate binder in intestinal tract
epakitin
41
reduces azotemia - "enteric dialysis"
azodyl
42
uses dietary supplements to bind or transform certain molecules so they no longer pass through the gut lining
enteric dialysis