Blood, Chemo, Misc

Question 1

Promote blood formation/ oxygen carrying potential

Answer 1

hematinics

Question 2

four kinds of heamtinics

Answer 2

iron compounds
erythropoietin
androgens
blood substitutes

Question 3

what species are iron compounds commonly used it

Answer 3

baby pigs - “thumps”

Question 4

what is erythropoietin used to treat

Answer 4

anemia due to chronic renal failure

Question 5

which hematinic is used for chronic renal failure but has inconsistent results

Answer 5

androgens

Question 6

blood substitute that is sometimes available in the US

Answer 6

oxyglobin

Question 7

two pathways for anticoagulants

Answer 7

intrinsic
extrinsic

Question 8

anticoagulant pathway that is activated by injury to the endothelial layer of a blood vessel

Answer 8

intrinsic

Question 9

anticoagulant pathway that is activated by injury to the tissue

Answer 9

extrinsic

Question 10

heparin prevents conversion of _______ to _______

Answer 10

prothrombin
thrombin

Question 11

EDTA prevents clotting by

Answer 11

chelation of calcium (factor IV)

Question 12

what kind of poisoning is EDTA used for

Answer 12

lead and other heavy metals

Question 13

what anticoagulant binds vitamin K

Answer 13

coumarin derivatitves

Question 14

what are Acid Citrate Dextrose, Citrate Phosphate Dextrose Adenine (ACD, CPDA-1) anticoagulants used for

Answer 14

blood transfusion bags/bottles

Question 15

two treatments uses for aspirin

Answer 15

prevent thromboembolism in heartworm treatment in dogs
feline cardiomyopathy

Question 16

two ways that hemostatics/anticoagulants antagonists can be used

Answer 16

topically
parentally

Question 17

what do topical hemostatics/anticoagulant antagonist provide

Answer 17

framework for the clot

Question 18

parental hemostatics/anticoagulant antagonists don’t directly activate what

Answer 18

the clot

Question 19

what do parental hemostatics/anticoagulant antagonists promote

Answer 19

synthesis of clotting factors

Question 20

what parental hemostatics/anticoagulant antagonists is used for heparin toxicity

Answer 20

protamine sulfate

Question 21

what parental hemostatics/anticoagulant antagonists is used for rodenticide ingestion

Answer 21

vitamin K1 (phytonadione)

Question 22

what parental hemostatics/anticoagulant antagonists is used to treat thrombocytopenia

Answer 22

aminocaproic acid

Question 23

what kind of drugs are used to Break/dissolve down thrombus or thromboembolism

Answer 23

fibrinolytic (thrombolytic)

Question 24

three treatments with fibrinolytics (thrombolytics)

Answer 24

Feline thromboembolism
Catheter thrombus
pulmonary thrombus

Question 25

four locations of rapidly dividing cells that are effected by chemo drugs

Answer 25

GI Hair Bone Marrow Reproductive

Question 26

two things that influence the effectiveness of chemo drugs

Answer 26

Length of time exposed Tumor resistance to drug (ie – Dose required)

Question 27

give chemo drugs in ______ doses more ______

Answer 27

smaller frequently

Question 28

for chemo drugs, use the ______ safe dose for a _____ period of time

Answer 28

maximum short

Question 29

chemo drugs are usually given in _____ with other drugs

Answer 29

combination

Question 30

how should all chemo drugs be dosed

Answer 30

body weight in kg to meter squared

Question 31

how do alkylating agents work as a chemo drug

Answer 31

cell cycle nonspecific chemo drug that stops DNA replication

Question 32

adverse effect of alkylating agents

Answer 32

Hemorrhagic cystitis

Question 33

what soil fungus are anthracyclines derived from

Answer 33

Fungus Streptomyces

Question 34

what kind of cancers are anthracyclines used for

Answer 34

lymphoproliferative cancers

Question 35

most commonly used chemo drug in vet med

Answer 35

doxorubicin (Adriamycin)

Question 36

why must you make sure you get anthracyclines in the vein on the first poke

Answer 36

they can cause very strong tissue damage in they leak out

Question 37

antimetabolites are cell cycle ______

Answer 37

specific

Question 38

what phase of DNA replication do antimetabolites effect

Answer 38

S phase

Question 39

four kinds of treatments that antimetabolite chemo drugs are used for

Answer 39

lymphoproliferative liver GI brain cancers

Question 40

what phase of DNA replication do antimetabolites effect

Answer 40

M phase

Question 41

antitubulin agents are plant alkaloids, derived from what plant

Answer 41

periwinkle (vinca rosea)

Question 42

agents that alter the relationship between the tumor and animal and improve the body's ability to fight it off on it's own

Answer 42

biologic response modifiers (BRMs)

Question 43

two types of biologic response modifiers (BRMs)

Answer 43

monoclonal antibodies interferon

Question 44

USDA approved drug for treatment of melanoma in dogs

Answer 44

canine melanoma vaccine

Question 45

what kind of tumors are platinum drugs used for and what species are they not for use in

Answer 45

solid tumors not for cats

Question 46

what enzyme is asparaginase extracted from

Answer 46

E. Coli

Question 47

what is asparaginase

Answer 47

an amino acid required by cancer cells

Question 48

what are glucocorticoids used for in cancer treatment

Answer 48

appetite stimulant

Question 49

NSAID drug that is used for bladder cancer treatment

Answer 49

Piroxicam (Feldene)

Question 50

five immune mediated diseases that immunosuppressive drugs are used for

Answer 50

Lupus Pemphigus IBD IMHA Rheumatoid arthritis

Question 51

a disease that causes blistering of the skin and the inside of the mouth, nose, throat, eyes, and genitals

Answer 51

pemphigus

Question 52

what is Azathioprine (Imuran) used in combination with

Answer 52

prednisone/prednisolone

Question 53

what species is Azathioprine (Imuran) not used in

Answer 53

no cats!

Question 54

what is cyclosporine derived from

Answer 54

fungus

Question 55

corticosteroids in low dose are ______ and high dose are ______

Answer 55

anti inflammatory immunosuppressive

Question 56

what is Oclacitinib (Apoquel) used for

Answer 56

pruritus in dogs older than 12 months of age