Urinary Problems Flashcards

1
Q

Criteria for definition of an AKI?

A

Rise in creatinine - >1.5 x from baseline within 7 days
OR - >26 micromol/L within 48hrs

AND Urine output <0.5mL/Kg for >6 hours

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2
Q

Pre-renal causes of AKI?

A

Generally due to hypoperfusion - secondary to..
Hypovolaemia - burns, D+V, major haemorrhage
Shock and reduced CO - sepsis, cardiac failure

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3
Q

Renal and post-renal causes of AKI?

A

Renal - Glomerular (tubular necrosis), interstitial (infection), vessels (vasculitis, HUS)

Post-renal - stones, stricture, malignancy, clots

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4
Q

Management principles of someone with AKI?

A

Treat underlying cause
Stop nephrotoxic meds - NSAIDs, ACEi, ARB, aminoglycoside
Optimise drug dosages for renal impairment
Treat hyperkalaemia - IV Insulin + glucose
Correct acidosis - IV sodium bicarbonate

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5
Q

Causes of acute urinary retention (AUR)

A

Men - BPH, prostate cancer, meatal stenosis

Women - prolapse, pelvic mass

Both - calculi, malignancy, stricture, faecal impaction

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6
Q

Investigations in AUR?

A

Abdo + genitourinary exam
PR - check anal tone, exclude impaction
Urine dipstick, renal USS
Serum Urea and creatinine

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7
Q

Management of AUR?

A

Bladder decompression - catheter / Supra-pubic

consider alpha blockers - Tamsulosin

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8
Q

Which investigations to order in renal colic?

A

Exclude infection - urinalysis and MSU
Bloods - U&Es, Calcium, phosphate, urate
KUB Xray

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9
Q

Management of renal colic

A

IV opioid analgesia +/- NSAID
PCNL - percutaneous nephrolithotomy

95% <5mm stones will pass spontaneously
>5mm - extracorporeal shockwave lithotripsy

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10
Q

Presentation and clinical features of testicular torsion

A

Sudden onset, severe testicular pain +/- abdo pain, N+V

High lying, horizontal testicle
Absent cremasteric reflex
no pain relief on elevating testicle (Epididymo-orchitis)

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11
Q

Investigations in testicular torsion

A

should really be a clinical diagnosis

Grey-scale ultrasound - whirlpool sign
Doppler USS of testicular blood flow

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12
Q

Management of Testicular torsion

A

Urgent surgical exploration and bilateral fixation of both testicles

If <6hrs - salvage rate 90-100%. If >24hrs, rate 0-10%

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13
Q

Investigations in UTI?

A

Dipstick –> +ve nitrites, leukocytes
Urine microscopy, culture and sensitivity if indicated

If pyelonephritis suspected, USS of upper UT

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14
Q

Indications for referral in UTI?

A

unresponsive to treatment
Hx of renal disease/anomaly
Recurrence in women despite preventative measures
Recurrence in men - 2+ episodes in 3 months
Haematuria

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15
Q

Which UTI medication is safe to take in pregnancy and when?

A

Trimethoprim: Safe in 3rd trimester/term - due to action as folate inhibitor unsafe in 1st/2nd trimester
–> do not take with methotrexate –> bone marrow suppression

Nitrofurantoin: Safe in 1st/2nd trimester, unsafe at term

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16
Q

Which drug should not be prescribed alongside Trimethoprim and why?

A

Methotrexate

Risk of dangerous bone marrow suppression