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Classification of AAA
Dilatation >3cm (normal 2cm) - any aneurysm is >50% original size of vessel
due to loss of elasticity and muscle cell degeneration
USS monitoring schedule for AAA?
3 - 4cm - annual
- 5 - 5.4 - 3 monthly
- 5cm+ - consider surgery
Triad of features of DKA?
Hyperglycaemia = >11mmol/L Acidosis = pH <7.3 OR Bicarb <15mmol/L Ketonaemia = 3+mmol/L or 2+ on standard urine dip
Presentation of DKA
polyuria, polydipsia, weakness, weight loss
pear drop acetone smell
Dry - membranes, turgor - hypovolaemic shock
Cerebral oedema in children
AKI due to hypovolaemia
Management of DKA
Rehydration with 0.9% sodium chloride
Insulin therapy - fixed rate IV infusion - 0.1 units/kg/hour
- see DKA charts for exact amounts
Maintain K+ between 4-5.5mmol/L
Switch fluids to dextrose once BM <12mmol/L to prevent hypos
What is Hyperglycaemic hyperosmolar state (HHS)?
+ clinical characteristics
Hyperglycaemia, in absence of ketogenesis –> leading to hyperosmolar state and severe volume depletion
Profound hyperglycaemia - >33mmol/L
Hyperosmolarity - >320mmol/Kg
Volume depletion with no acidosis - pH >7.3, Bicarb >15
Management of HHS
IV fluid therapy - 0.9% sodium chloride
If glucose not sufficiently lowered with just fluids, use low dose insulin infusion (0.05 units/kg/hr)
Investigations in seizures
Exclude other non-epileptic causes: Infection Electrolyte imbalance Toxicology screen Head injury/SoL - Head CT Hypoglycaemia
EEG only useful if actively seizing
Management ladder in seizures
1) make the area safe, protect the head, START TIMER
2) Buccal Midazolam
3) 5mins - Rectal diazepam, 2nd dose after 5 mins, call ambulance
4) Phenytoin/phenobarbital
5) Paraldehyde
6) RSI - GA with thiopentone
What is the FAST Test
Face - facial movements
Arms - brief test of power/sensation in the arms
Speech - repeat a sentence - look for slurring, wrong words
Timing - call ambulance/get to hospital if suspected stroke
Management of confirmed non-haemorrhagic stroke
Aspirin 300mg, for 2 weeks - then switch onto long term antithrombotic + PPI cover
+ Clopidogrel 75mg/OD
2nd line Dipyridamole
Thrombolysis - Alteplase - most effective if <90 mins
+ Post lysis CT scan to confirm no bleeding
Timing of investigations at presentation to ED
CT/MRI within 25 minutes
Administration of Alteplase within 60 minutes
If symptoms more prolonged - CT/MRI within 24hrs
Long term therapy after a stroke?
Confirmed no AF - Clopidogrel 75mg, OD. 2nd line dipyridamole 200mg BD
+ Lipid modification - high dose statin Atorvastatin 20-80mg
With AF - Aspiring 300mg for 2 weeks, then switch to Warfarin, (and then to DOAC) - target INR 2.5 (2-3)
Investigations in syncope?
12 lead ECG Bloods baseline - Hb, glucose, electrolytes Cardiac enzymes, D-dimer BP lying and standing Cardio/neuro exam
Aims of therapy in DKA?
Drop glucose by >3/hr, until <14 - then switch to dextrose
Drop Ketones 0.5/hr until <0.6
Rise Bicarb >3/hr until >15
Switch to S/C insulin with E+D, pH >7.3 and Ketones <0.6