Urinary Medications

Question 1

Trimethoprim-sulfamethoxazole (Bactrim)

Answer 1

First-line for lower UTI

Contraindicated if sulfa allergy

Question 2

ciprofloxacin

Answer 2

For lower UTI

For patients with sulfa allergy

Question 3

nitrofurantoin (Macrobid)

Answer 3

For recurrent lower UTIs

Question 4

phenazopyridine (Pyridium)

Answer 4

Indication: UTI pain relief
MOA: local analgesic effect
SE: well-tolerated, reddish-orange urine

Question 5

mirabegron

Answer 5

Class: beta-3-adrenergic agonist/anti-spasmodic
MOA: selectively stimulates beta-3-adrenergic receptors—relaxing bladder smooth muscle
Indication: overactive bladder
SE: hypertension, urinary retention, UTI, headache
Given PO

Question 6

oxybutynin

Answer 6

MOA: anti-cholinergic; inhibits actions of acetylcholine
Indication: overactive bladder, urinary incontinence
SE: dry mouth, constipation
Only given PO (can be ER)