Urinary incontinence and pelvic organ prolapse - NICE 2019 Flashcards

1
Q

3 main types of incontience

A

Stress UI
Mixes
Urgency/Overreactive bladder OAB

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2
Q

History for urinary incontience

A
  • Frequency/nocturia
  • Urgency, urge UI
  • Stress UI, ?continous (fistula)
  • Voiding - hesitant, poor stream, intermittent stream
  • Post-micturation - incomplete empty, dribbling
  • Haematuria, pain (bladder/urethral)
  • Bowel Sx
  • medical Hx
  • Surgical Hx
  • O&G Hx - ?completed family, sexual dysfunction
  • Drug Hx
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3
Q

Examination

A

AMTS
Abdo examination (masses
Bimanual +/- PR

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4
Q

Investigations for incontience

A

MSU
Residual volume - USS or catheter post void
Bladder diary for 3/7
Symptom score

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5
Q

If urinalysis shows leukocytes and nitrites +ve

A

Await MSU, if +ve treat

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6
Q

When to perform urodynamic testing?

A

Do not perform for primary stress incontinence before surgery

Perform if stress and :
- Urge-predominant, or unclear
- Voiding dysfunction
- Anterior or apical prolapse
- Hx of previous surgery for SUI

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7
Q

Lifestyle advice to give for urinary incontience

A

Less caffeine
Drink 1-2 L fluid/day
If BMI >30 lose weight

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8
Q

How long and how often should pelvic floor muscle training for stress/mixed UI

A

3 months
8 contractions at least TDS

4 months if POP

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9
Q

For how long should bladder retraining take place for OAB or mixed

A

Minimum 6 weeks

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10
Q

2 terms used with overactive bladder if accompanied with incontinece or not

A

OAB dry or wet

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11
Q

If urodynamic being used how is detrusor overactivity diagnosed?

A

Diagnosis is therefore made at filling cystometry:


a) Rise in detrusor pressure of >15cm H2O

b) Rise in detrusor pressure of <15cm H2O in the presence of urgency or urge incontinence



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12
Q

What drugs are offered 1st line in OAB

A

Oxybutynin
Tolteradone
Solifenacin/Darifenacine

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13
Q

What proportion of women have improve symptoms after anticholinergics?

A

57-71% of women,

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14
Q

Side effects of anti-cholinergics

A

Nausea, constipation, diarrhoea and abdominal discomfort

Dry mouth (88%)

Blurred vision

Voiding difficulties

Headache, dizziness, drowsiness, restlessness and disorientation

Rash, dry skin, photosensitivity

Arrhythmia

Angioedema



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15
Q

When are anticholinergics contraindicated?

A

Glaucoma
Ulcerative colitis
Myasthenia gravis
Intestinal obtruciton

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16
Q

When should you not given oxybutynin

A

Avoid if >80yrs or frail
Can consider transdermal

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17
Q

Which anticholinergic has the least confusion side effects and can be consider in women with dementia

A

Darifenacin

18
Q

When to review after start anticholinergic

A

4 weeks
Long term & >75 review every 6 months

19
Q

When to consider desmopressin

A

nocturia and nocturnal enuresis.

20
Q

When is desmopressin contraindicated and side effects

A

Congestive heart failure, caution if 65+ with CVD or HTN

Side-effects include fluid retention with hyponatraemia, epistaxis, nasal congestion and rhinitis with nasal spray


21
Q

If antimuscarinic contraindicated, what medication to consider?

A

Mirabegron

22
Q

What type of drug is mirabegron

A

Selective B-3 adrenergic agonist

23
Q

If medication not controlling overactive bladder symptoms what is the next step?

A

Refer to MDT to discuss

24
Q

What ti explain to patient before Bladder wall injection with botox A

A
  1. the likelihood of complete or partial symptom relief
  2. clean intermittent catheterisation, the risks, and how long it might need to be continued
  3. the risk of adverse effects, including an increased risk of urinary tract infection
  4. Not much evidence about how long the injections work for, how well they work in the long term and their long-term risks*
25
Q

How much botox to give at initially, when to review

A

100 units botox A
Review in 12 months

Can increase two 200 if limited response

26
Q

Whe to offer posterior sacral nerve stimulation

A

Declined or no response to botox

27
Q

What very rare surgical options can be considered for OAB

A

Augmentation cystoplasty - surgery to enlarge bladder

Urinary diversion

28
Q

What proportion of stress incontience can be managed with conservative measures

A

50%

29
Q

When should be referred to MDT

A

When conservative measures fail to work

30
Q

Main surgical treatments of stress incontience

A
  1. Open/Lap Burch Colposuspension
  2. Autologous recurs fascial sling/Retropubuic mid-urethral mesh sling

Bulking agents
Deloxetine

31
Q

Conservative treatments of prolapse

A

losing weight, if the woman has a BMI greater than 30 kg/m2
minimising heavy lifting
preventing or treating constipation
Topical oestrogen - if signs of atrophy or consider oestrogen ring
Pelvic floor training - 4months
Pessaries

32
Q

How often should pessaries be removed and inspected

A

6 months

33
Q

For prolapse and does not mind if retains uterus, what surgeries can be offered?

A

vaginal hysterectomy, with or without vaginal sacrospinous fixation with sutures or

vaginal sacrospinous hysteropexy with sutures or

Manchester repair.

34
Q

For prolapse would like to retain uterus, what surgeries can be offered?

A

vaginal sacrospinous hysteropexy with sutures or

Manchester repair (unless want children)

35
Q

What is a Manchester repair?

A

excision of the elongated cervix and approximation of the cardinal ligaments anterior to the cervix to elevate and retract it so that the uterus is both anteverted and supported

36
Q

What surgery can be offered to anterior or posterior repair?

A

Anterior: Anterior repair without mesh
Posterior: Posterior repair without mesh

Review in 6 months

37
Q

If women has mesh complication what can offer as management

A

Consider topical oestrogen cream if exposed area <1cm, FU 3 months

removal has limited benefits, may worsen pain, UI or prolapse may recur

Consider partial/complete removal if
- Does not want topical oestrogen, area of exposure >1cm, gainful mesh extrusion, no response in 3 months

38
Q

Sacrocolpopexy

A

Surgery to treat vault prolapse, plastic mesh used to attach vagina to sacrum

39
Q

Sacro-hysteropexy

A

Uterine prolapse, plastic mesh from womb to sacrum

40
Q

Vaginal sacrospinous fixation

A

Vaginal vault or uterine prolapse - top of vagin stitched to sacrospinous ligament

41
Q

Vaginal sacrospinous hysteropexy

A

Used to treat uterine prolapse - cervix stitched to sacrospinous ligament