Urinary Incontinence

Question 1

What drug is used to treat bladder atony? What is it usually combined with? Effect?

Answer 1

bethanechol (Urecholine) is a strong muscarinic agent that stimulates cholinergic receptors on detrusor. When combined with Phenoxybenzamine, it can increase urethrogram due to a weak nicotinic effect

Question 2

What drug is used to treat urethral outflow obstruction (upper motor neuron disease)? What type of drug is it? Effect?

Answer 2

Phenoxybenzamine (Dibenzyline), an a-adrenergic antagonist. Allows relaxation of internal urethral sphincter

Question 3

What drug is used to treat urge incontinence and cats with FLUTD? What type of drug is it?

Answer 3

Oxybutinin (Ditropan). An anticholinergic and antispasmodic

Question 4

What drug is used to treat urge incontinence? What type of drug is it? Effect?

Answer 4

An anticholinergic that reduces muscle contractions allowing better bladder filling

Question 5

What is a substitute for Phenylpropanolamine?

Answer 5

Ephedrine/pseudoephedrine

Question 6

What is the drug of choice for treating urethral sphincter mechanism incontinence? What type of drug is it? Effect? What are the two side effects?

Answer 6

Phenylpropanolamine (PPA) - an a-adrenergic agonist increases internal sphincter tone. Side effects include hypertension and hyperactivity