Uric Acid Metabolism Flashcards
reference interval of uric acid in female
1.5 - 6mg/dl
reference interval of uric acid in males
2.5 - 7mg/dl
uric acid is a.k.a
7,9 dihydro1H-purine
weight - 168Da
uric acid exists as mono sodium irate at what Ph?
5.57 & above
ph at which mono sodium urate crystallizes out of solution;
7.0 - 7.2
these crystals are called
Toph i
what is pseudo gout ?
a lesion triggered by deposition of calcium pyrophosphate crystals on joint cavities
formation of uric acid stones is called
Urolithiasis
if Uricacid/creatinine ratio is >0.7 it is
hyperuricaemia
if Uricacid/creatinine ratio is <0.7 it is
renal failure due to intrinsic kidney disease
uricosurics include
1) probenicid
2) sulphinpyrazone
hypouricaemia is uric acid levels
<2.0 mg/dl (0.12mmol/l)