Uric Acid Metabolism Flashcards

1
Q

reference interval of uric acid in female

A

1.5 - 6mg/dl

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2
Q

reference interval of uric acid in males

A

2.5 - 7mg/dl

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3
Q

uric acid is a.k.a

A

7,9 dihydro1H-purine

weight - 168Da

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4
Q

uric acid exists as mono sodium irate at what Ph?

A

5.57 & above

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5
Q

ph at which mono sodium urate crystallizes out of solution;

A

7.0 - 7.2

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6
Q

these crystals are called

A

Toph i

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7
Q

what is pseudo gout ?

A

a lesion triggered by deposition of calcium pyrophosphate crystals on joint cavities

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8
Q

formation of uric acid stones is called

A

Urolithiasis

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9
Q

if Uricacid/creatinine ratio is >0.7 it is

A

hyperuricaemia

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10
Q

if Uricacid/creatinine ratio is <0.7 it is

A

renal failure due to intrinsic kidney disease

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11
Q

uricosurics include

A

1) probenicid
2) sulphinpyrazone

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12
Q

hypouricaemia is uric acid levels

A

<2.0 mg/dl (0.12mmol/l)

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